About ResLit
ResLit is a comprehensive, curated database of antimicrobial resistance (AMR) genes and mutations extracted from peer-reviewed scientific literature.
Our Mission
Antimicrobial resistance (AMR) is one of the most pressing global health challenges of our time. Understanding the genetic basis of resistance is crucial for developing new treatments and surveillance strategies.
ResLit aims to bridge the gap between scientific literature and actionable knowledge by systematically extracting, curating, and organizing information about AMR genes and mutations from PubMed publications.
Our database is designed to be a resource for researchers, clinicians, and public health professionals working to combat antimicrobial resistance.
How It Works
We systematically search PubMed for publications describing antimicrobial resistance genes and mutations, using targeted search strategies.
Key information including gene names, mutations, organisms, antibiotics, and geographic locations are extracted from each publication.
Each entry is reviewed by expert curators who validate the information and add additional context and annotations.
Data Coverage
- Beta-lactamasesTEM, CTX-M, NDM, KPC, OXA
- Aminoglycosidesaac, aph, ant, armA
- Fluoroquinolonesqnr, aac(6')-Ib-cr
- GlycopeptidesvanA, vanB, vanC
- And more...Macrolides, Tetracyclines, Polymyxins
- SubstitutionSingle amino acid changes
- InsertionAmino acid insertions
- DeletionAmino acid deletions
- FrameshiftReading frame alterations
How to Cite
If you use ResLit in your research, please cite:
Start Exploring
Browse our curated database of AMR genes and mutations, or learn how you can contribute as a curator.