Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
Beta-lactamase genes of the penicillin-susceptible Bacillus anthracis Sterne strain.
The penicillin-susceptible Bacillus anthracis Sterne strain encodes two beta-lactamase genes, bla1 and bla2, which confer resistance to ampicillin and cephalosporins when cloned in E. coli and Bacillus subtilis.
Beta-lactamase gene expression in a penicillin-resistant Bacillus anthracis strain.
The study identifies bla1 and bla2 beta-lactamase genes in a penicillin-resistant Bacillus anthracis strain, with bla1 being the major contributor to ampicillin resistance. Both genes contribute to resistance against several beta-lactam antibiotics.
Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in Bacillus anthracis.
The study identifies mutations in the rsiP gene that are associated with penicillin resistance in Bacillus anthracis, but not all strains with these mutations exhibit resistance.
The roles of antimicrobial resistance, phage diversity, isolation source and selection in shaping the genomic architecture of Bacillus anthracis.
The study identifies ten AMR genes in B. anthracis, highlighting their distribution across global isolates and their association with population genomic structure. Key genes include mph L, bla 1, fos B, bla 2, vml R, bcII, tem -116, cfr C, dfr G, and oxa -59, each with distinct resistance mechanisms and geographic prevalence.
Identification of the Extracytoplasmic Function σ Factor σ(P) Regulon in Bacillus thuringiensis.
The study identifies four beta-lactamases (Bla1, Bla2, Bla3, Bla4) and two penicillin-binding proteins (PbpN and DacC) regulated by σ P in Bacillus thuringiensis, which contribute to resistance against various β-lactam antibiotics.
Comparative Analysis of Bacillus cereus Group Isolates' Resistance Using Disk Diffusion and Broth Microdilution and the Correlation between Antimicrobial Resistance Phenotypes and Genotypes.
The study identified several antimicrobial resistance genes in Bacillus cereus group isolates, including beta-lactamase-encoding genes (bla1, blaZ, blaTEM), mph for erythromycin resistance, rph for rifampicin resistance, and fosB for fosfomycin resistance. These genes were detected using ABRIcate and MEGARes 2.0 database, and their association with resistance phenotypes was analyzed.
β-Lactam Resistance in Azospirillum baldaniorum Sp245 Is Mediated by Lytic Transglycosylase and beta-lactamase and Regulated by a Cascade of RpoE7→RpoH3 Sigma Factors.
The study identifies bla1 as a functional beta-lactamase gene in Azospirillum baldaniorum Sp245 that confers ampicillin resistance. The gene is regulated by a cascade involving RpoE7 and RpoH3 sigma factors.
Meat and meat products as potential sources of emerging MDR Bacillus cereus: groEL gene sequencing, toxigenic and antimicrobial resistance.
The study identified multiple antimicrobial resistance genes, including bla1, bla2, ermA, tetA, and tetB, in multidrug-resistant Bacillus cereus isolates from meat and meat products.
Emergence of multidrug-resistant Bacillus spp. derived from animal feed, food and human diarrhea in South-Eastern Bangladesh.
The study identifies multiple AMR genes in Bacillus spp. isolated from animal feed, food, and human diarrhea in Bangladesh, highlighting the prevalence of multidrug resistance and the need for monitoring in the agricultural and food sectors.
Genomic characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic insights into Nocardia cyriacigeorgica.
The study identified several antimicrobial resistance genes in Nocardia cyriacigeorgica, including VanSO and VanRO for vancomycin resistance, erm(O)-Irm, srmB, and ermH for macrolide resistance, bla1 and bcl for beta-lactam resistance, CTX-M and KPC for cephalosporin and carbapenem resistance, tetA(58) and tetB(58) for tetracycline resistance, folC and folP for sulfonamide resistance, rbpA and rpoB2 for rifamycin resistance, murA and AbaF for fosfomycin resistance, cmlR for chloramphenicol resistance, and VatF and VatE for streptogramin resistance.
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