Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
chloramphenicol efflux protein
Overview
SGI2, a Relative of Salmonella Genomic Island SGI1 with an Independent Origin
The study identifies SGI2, a genomic island in Salmonella enterica serovar Emek, which contains the cmlA9 and floR genes conferring resistance to chloramphenicol, florfenicol, and tetracycline. SGI2 has an independent origin from SGI1, with the integron located in a different position and showing sequence differences in the backbone.
Characterization of a transmissible plasmid encoding VEB-1 and VIM-1 in Proteus mirabilis.
Scarless Removal of Large Resistance Island AbaR Results in Antibiotic Susceptibility and Increased Natural Transformability in Acinetobacter baumannii.
The study shows that removing the AbaR resistance island from Acinetobacter baumannii restores antibiotic susceptibility and increases natural transformability. Several AMR genes within AbaR were identified, including aadB, aacC1, aphA1b, aacA, aadA1, strA, strB, blaVEB-1, blaOXA-10, sul1, dhfrI, dhfrX, tetA(A), tetA(G), cmlA1, cmlA5, cmlA9, catA1, arr-2, and sup.
Genomic Identification of Multidrug-Resistant Salmonella Virchow Monophasic Variant Causing Human Septic Arthritis.
The study identifies a multidrug-resistant Salmonella Virchow monophasic variant (Salmonella 6,7,14:r:-) that exhibits resistance to chloramphenicol, tetracycline, trimethoprim, sulfamethoxazole, and nalidixic acid. The resistance is conferred by the presence of cmlA9, drfA1, sul1, tetA(G), and a gyrA(S83F) mutation.
Domestically Acquired NDM-1-Producing Pseudomonas aeruginosa, Southern California, USA, 2023
The study reports a case of domestically acquired NDM-1-producing Pseudomonas aeruginosa in a transplant patient in southern California, highlighting the presence of multiple resistance genes including blaNDM-1, blaOXA-10, blaOXA-488, blaPDC-35, blaPME-1, aac(6')-Ib9, ant(3”)-IIa, aph(3′)-IIb, aph(3′)-VIa, catB3, catB7, cmlA9, fosA, tet(D), and sul1.
Phenotypic and genomic characterization of Pseudomonas aeruginosa isolates recovered from catheter-associated urinary tract infections in an Egyptian hospital.
The study identified multiple AMR genes and mutations in Pseudomonas aeruginosa isolates from catheter-associated urinary tract infections in Egypt, including beta-lactamases, aminoglycoside-modifying enzymes, quinolone resistance proteins, and efflux pump systems. Additionally, a pBT2436-like megaplasmid was detected, which contributes to multidrug resistance.
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