PA2019

Resistance–Nodulation-Cell division (RND) multidrug efflux membrane fusion protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to PA2019

Browse AMR rules for PA2019

Overview

Drug Classes: amikacin, ceftazidime, aztreonam, gentamicin, ciprofloxacin
Papers: 1
Mutations: 3

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
W358R	-	-	-	amikacinceftazidimeaztreonam+2 more	Reslit	Candidate
L331V	-	-	-	amikacinceftazidimeaztreonam+2 more	Reslit	Candidate
K329Q	-	-	-	amikacinceftazidimeaztreonam+2 more	Reslit	Candidate

Papers1

1

Next generation sequencing reveals the antibiotic resistant variants in the genome of Pseudomonas aeruginosa.

Research Article

PMID 28797043 · 2017

Mutation Information

PA2019: p.W358R PA2019: p.L331V PA2019: p.K329Q

Protein Change: W358R, L331V, K329Q
Confers Resistance To: amikacinceftazidimeaztreonamgentamicinciprofloxacin
Validation Method: whole genome sequencing
Source Database: Reslit