Browse AMR Genes

Explore antimicrobial resistance genes from the literature

Rv2731

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to Rv2731

Browse AMR rules for Rv2731

Overview

Drug Classes: Pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
P82T	-	single resistance variant	Mycobacterium tuberculosis	Pyrazinamide	Card Database	Established
F89L	-	single resistance variant	Mycobacterium tuberculosis	Pyrazinamide	Card Database	Established

Papers1

1

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

PMID 30337678 · 2018

Mycobacterium tuberculosis Rv2731 mutations confer resistance to pyrazinamide; CARD accession: CARD:3004987

Mutation Information

Rv2731: p.P82T Rv2731: p.F89L

Protein Change: P82T, F89L
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Pyrazinamide
Effect on Function: single resistance variant
Source Database: Card Database