ResLit

aac(2')-Ic

aminoglycoside N-acetyltransferase AAC(2')-Ic

NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to aac(2')-Ic
AMR Rules
Browse AMR rules for aac(2')-Ic
Curation StatusNot Validated

Overview

Drug Classes
TOBRAMYCIN, GENTAMICIN
Organisms
Mycobacterium tuberculosis H37Rv
Papers
1
Papers1
1

Aminoglycoside 2'-N-acetyltransferase genes are universally present in mycobacteria: characterization of the aac(2')-Ic gene from Mycobacterium tuberculosis and the aac(2')-Id gene from Mycobacterium smegmatis.

PMID 9159528 · 1997

Gene Information

Gene Name
aac(2')-Ic
Allele
AAC(2')-Ic
Encodes
aminoglycoside N-acetyltransferase AAC(2')-Ic

Mechanism

antibiotic inactivation

Confers Resistance To

TOBRAMYCINGENTAMICIN

Organisms Tested In

• Mycobacterium tuberculosis H37Rv
2

Aminoglycoside 2'-N-acetyltransferase genes are universally present in mycobacteria: characterization of the aac(2')-Ic gene from Mycobacterium tuberculosis and the aac(2')-Id gene from Mycobacterium smegmatis.

PMID 9159528 · 1997

Gene Information

Gene Name
aac(2')-Ic
Allele
AAC(2')-Ic
Encodes
aminoglycoside N-acetyltransferase AAC(2')-Ic

Mechanism

antibiotic inactivation

Confers Resistance To

TOBRAMYCINGENTAMICIN

Organisms Tested In

• Mycobacterium tuberculosis H37Rv
3

Aminoglycoside 2'-N-acetyltransferase genes are universally present in mycobacteria: characterization of the aac(2')-Ic gene from Mycobacterium tuberculosis and the aac(2')-Id gene from Mycobacterium smegmatis.

PMID 9159528 · 1997

Gene Information

Gene Name
aac(2')-Ic
Allele
AAC(2')-Ic
Encodes
aminoglycoside N-acetyltransferase AAC(2')-Ic

Mechanism

antibiotic inactivation

Confers Resistance To

TOBRAMYCINGENTAMICIN

Organisms Tested In

• Mycobacterium tuberculosis H37Rv
4

Aminoglycoside 2'-N-acetyltransferase genes are universally present in mycobacteria: characterization of the aac(2')-Ic gene from Mycobacterium tuberculosis and the aac(2')-Id gene from Mycobacterium smegmatis.

PMID 9159528 · 1997

Gene Information

Gene Name
aac(2')-Ic
Allele
AAC(2')-Ic
Encodes
aminoglycoside N-acetyltransferase AAC(2')-Ic

Mechanism

antibiotic inactivation

Confers Resistance To

TOBRAMYCINGENTAMICIN

Organisms Tested In

• Mycobacterium tuberculosis H37Rv
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