Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
N-acetyltransferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AAC(3)-IIc | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 13 | Aminoglycoside, Gentamicin +9 |
| India, China, Amazon River|Kalamas River|Cam River|Cambridge|Amazon River Plume, Germany|Lower Saxony|North-Rhine-Westphalia |
| 2010, 2015, 2018, 2019, 2020, 2021, 2023, 2024, 2025 |
| JSXJ00000000 |
| CAA38525.1 |
| aac(3)-IIc | ResFinder Database | 1 | TOBRAMYCIN, SISOMICIN +4 | Escherichia coli | - | - | X54723 | - |
Aminoglycoside modifying enzymes.
The paper discusses various aminoglycoside modifying enzymes, particularly focusing on AAC(6')-Ib, AAC(6')-Ib-cr, and AAC(6')-Ib 11, which confer resistance to aminoglycosides like amikacin and gentamicin, and in some cases, quinolones.
Genomic and Functional Portrait of a Highly Virulent, CTX-M-15-Producing H30-Rx Subclone of Escherichia coli Sequence Type 131.
The study identifies the CTX-M-15 beta-lactamase gene and other resistance genes such as strA, strB, and aac(3)-IIC in the H30-Rx subclone of E. coli ST131, highlighting its multidrug-resistant nature.
Characterization of antimicrobial resistance genes in Haemophilus parasuis isolated from pigs in China.
The study identified multiple antimicrobial resistance genes in Haemophilus parasuis isolates from pigs in China, including blaTEM-1, blaROB-1, ermB, ermA, flor, catl, tetB, tetC, rmtB, rmtD, aadA1, aac(3′)-IIc, sul1, and sul2. Additionally, mutations in the gyrA and parC genes were associated with fluoroquinolone resistance.
Interplay Between the Phenotype and Genotype, and Efflux Pumps in Drug-Resistant Strains of Riemerella anatipestifer.
The study identified multiple AMR genes and mutations in Riemerella anatipestifer, including aac(6')-Ib, aadA1, aadA2, aadA5, aac(3')-IIc, aac(3')-IV, aph(3')-VII, aph(2')-Ib, bla TEM, bla OXA, tet(A), tet(B), sul1, sul2, sul3, cat2, cmlA, floR, emrF, qnrS, and qnrD. Additionally, mutations in gyrA and parC were found to confer fluoroquinolone resistance.
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection.
The study presents a nanopore metagenomics method for rapid detection of bacterial pathogens and antibiotic resistance genes in lower respiratory infections, achieving high sensitivity and specificity through host DNA depletion and real-time sequencing.
Characterization of Discriminatory Antimicrobial Resistance Genes in Aquatic Environments Using Machine Learning
The study identifies discriminatory antibiotic resistance genes (ARGs) using an extremely randomized tree (ERT) algorithm, highlighting genes like sul1, tet(W), and ermB as significant markers for differentiating resistomes across various aquatic environments.
Carbapenem-Resistant Enterobacter hormaechei ST1103 with IMP-26 Carbapenemase and ESBL Gene bla (SHV-178).
The study identifies a multidrug-resistant Enterobacter hormaechei strain L51 carrying the bla IMP-26 carbapenemase gene and bla SHV-178 ESBL gene, along with other resistance genes on a conjugative IncHI2/2A plasmid.
The Animal-foods-environment interface of Klebsiella pneumoniae in Germany: an observational study on pathogenicity, resistance development and the current situation.
The study identifies several AMR genes, including bla CTX-M-15, bla OXA-48, bla SHV-1, bla SHV-2, bla SHV-27, bla TEM-1, aac(3)-IIc, qnrS1, and mcr-1, in Klebsiella pneumoniae isolates from various non-human sources in Germany. Fluoroquinolone resistance was associated with mutations in GyrA and ParC.
Four novel Acinetobacter lwoffii strains isolated from the milk of cows in China with subclinical mastitis.
Four Acinetobacter lwoffii strains were isolated from the milk of cows with subclinical mastitis in China. These strains exhibited multidrug resistance and carried 17 resistance genes, including beta-lactamase, aminoglycoside-modifying, fluoroquinolone, tetracycline, sulfonamide, and chloramphenicol resistance genes.
Antimicrobial Resistance and Genomic Characterization of an Escherichia coli Strain Harboring p0111 and an IncX1-Type Plasmid, Isolated from the Brain of an Ostrich.
The study identifies multiple antimicrobial resistance genes in an Escherichia coli strain isolated from an ostrich, including bla CTX-M-55, rmtB, sul1, APH(6)-Id, tet(A), AAC(3)-IIc, aadA2, bla TEM-1B, and floR, which confer resistance to various antibiotics such as cephalosporins, aminoglycosides, sulfonamides, tetracyclines, and chloramphenicol.
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