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aac(3)-VIII

aminoglycoside N-acetyltransferase AAC(3)-VIII

NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to aac(3)-VIII
AMR Rules
Browse AMR rules for aac(3)-VIII
Validation StatusConfirmed2+ DBs

Overview

Mechanism
Enzymatic modification
Drug Classes
AMINOGLYCOSIDE, UNKNOWN AMINOGLYCOSIDE
Organisms
Streptomyces fradiae, Streptomyces ribosidificus
Alleles
2
Papers
3
Databases
Card DatabaseReference Gene CatalogResFinder Database
Allele Variants2
AlleleDatabasePapersDrug ClassesOrganismsCountriesYearsSequence AccessionProtein Accession
AAC(3)-VIII
Reference Gene CatalogResFinder Database
8AMINOGLYCOSIDE, UNKNOWN AMINOGLYCOSIDEStreptomyces fradiae +1-2005AJ843080.1CAH58703.1
AAC(3)-VIIIa
Card DatabaseReference Gene Catalog
4AMINOGLYCOSIDEStreptomyces fradiae-1991M55426.1AAA26685.1
Papers3
1

The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.

PMID 15827636 · 2005

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
Reference Gene Catalog
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
AJ843080.1
Protein Accession
CAH58703.1
2

The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.

PMID 15827636 · 2005

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
Reference Gene Catalog
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
AJ843080.1
Protein Accession
CAH58703.1
3

The ribostamycin biosynthetic gene cluster in Streptomyces ribosidificus: comparison with butirosin biosynthesis.

PMID 16258246 · 2005

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
ResFinder Database
Mechanism
Enzymatic modification
Confers Resistance To
UNKNOWN AMINOGLYCOSIDEAMINOGLYCOSIDE
Organisms Tested In
• Streptomyces ribosidificus
Sequence Accession
AJ748131.1
Protein Accession
CAG34706.1
Notes
Chromosomal in Streptomyces ribosidificus
4

The ribostamycin biosynthetic gene cluster in Streptomyces ribosidificus: comparison with butirosin biosynthesis.

PMID 16258246 · 2005

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
ResFinder Database
Mechanism
Enzymatic modification
Confers Resistance To
UNKNOWN AMINOGLYCOSIDEAMINOGLYCOSIDE
Organisms Tested In
• Streptomyces ribosidificus
Sequence Accession
AJ748131.1
Protein Accession
CAG34706.1
Notes
Chromosomal in Streptomyces ribosidificus
5

The ribostamycin biosynthetic gene cluster in Streptomyces ribosidificus: comparison with butirosin biosynthesis.

PMID 16258246 · 2005

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
Reference Gene Catalog
Mechanism
Enzymatic modification
Confers Resistance To
UNKNOWN AMINOGLYCOSIDEAMINOGLYCOSIDE
Organisms Tested In
• Streptomyces ribosidificus
Sequence Accession
AJ748131.1
Protein Accession
CAG34706.1
Notes
Chromosomal in Streptomyces ribosidificus
6

The ribostamycin biosynthetic gene cluster in Streptomyces ribosidificus: comparison with butirosin biosynthesis.

PMID 16258246 · 2005

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
Reference Gene Catalog
Mechanism
Enzymatic modification
Confers Resistance To
UNKNOWN AMINOGLYCOSIDEAMINOGLYCOSIDE
Organisms Tested In
• Streptomyces ribosidificus
Sequence Accession
AJ748131.1
Protein Accession
CAG34706.1
Notes
Chromosomal in Streptomyces ribosidificus
7

Characterisation of aminoglycoside acetyltransferase-encoding genes of neomycin-producing Micromonospora chalcea and Streptomyces fradiae.

PMID 2060791 · 1991

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIIIa
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIIIa, AAC(3)
Source Database
Card Database
Mechanism
antibiotic inactivation
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
M55426.1
Protein Accession
AAA26685.1
Notes
ARO:3002542
8

Characterisation of aminoglycoside acetyltransferase-encoding genes of neomycin-producing Micromonospora chalcea and Streptomyces fradiae.

PMID 2060791 · 1991

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIIIa
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIIIa
Source Database
Reference Gene Catalog
Mechanism
antibiotic inactivation
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
M55426.1
Protein Accession
AAA26685.1
Notes
ARO:3002542
9

Characterisation of aminoglycoside acetyltransferase-encoding genes of neomycin-producing Micromonospora chalcea and Streptomyces fradiae.

PMID 2060791 · 1991

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIIIa
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIIIa, AAC(3)
Source Database
Card Database
Mechanism
antibiotic inactivation
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
M55426.1
Protein Accession
AAA26685.1
Notes
ARO:3002542
10

Characterisation of aminoglycoside acetyltransferase-encoding genes of neomycin-producing Micromonospora chalcea and Streptomyces fradiae.

PMID 2060791 · 1991

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIIIa
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIIIa
Source Database
Reference Gene Catalog
Mechanism
antibiotic inactivation
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
M55426.1
Protein Accession
AAA26685.1
Notes
ARO:3002542
11
PMID N/A

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
Reference Gene Catalog
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
AB211959.1
Protein Accession
BAD95833.1
12
PMID N/A

Gene Information

Gene Name
aac(3)-VIII
Allele
AAC(3)-VIII
Encodes
aminoglycoside N-acetyltransferase AAC(3)-VIII
Source Database
Reference Gene Catalog
Confers Resistance To
AMINOGLYCOSIDE
Organisms Tested In
• Streptomyces fradiae
Sequence Accession
AB211959.1
Protein Accession
BAD95833.1
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