aac(6')-Iak

aminoglycoside N-acetyltransferase AAC(6')-Iak

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic inactivation
Validation Method: plasmid transformation and MIC testing
Drug Classes: AMINOGLYCOSIDE, neomycin, netilmicin, sisomicin, tobramycin, AMIKACIN, DIBEKACIN
Organisms: Stenotrophomonas maltophilia AU12-09, Stenotrophomonas maltophilia, Stenotrophomonas maltophilia IOMTU250, Escherichia coli DH5α
Geographic Location: Nepal
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia AU12-09
Sequence Accession: APIT01000070.1
Protein Accession: EMI48985.1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: JVZQ01000186.1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: JZIW01000001.1
Protein Accession: KOO82158.1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: JZTX01000001.1
Protein Accession: KOO79896.1

Identification of a novel 6′-N-aminoglycoside acetyltransferase, AAC(6′)-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

The study identifies a novel 6′-N-aminoglycoside acetyltransferase, AAC(6′)-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia, which confers resistance to several aminoglycosides.

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: 6′-N-aminoglycoside acetyltransferase
Source Database: Reslit
Confers Resistance To: neomycinnetilmicinsisomicintobramycin
Organisms Tested In: • Stenotrophomonas maltophilia IOMTU250
• Escherichia coli DH5α
Geographic Location: Nepal
Validation Method: plasmid transformation and MIC testing
Sequence Accession: AB894482

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AB894482.1
Protein Accession: BAO21229.1
Notes: ARO:3003199

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak, AAC(6')
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AB894482.1
Protein Accession: BAO21229.1
Notes: ARO:3003199

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: aac(6')-Iak
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: TOBRAMYCINAMIKACINSISOMICINDIBEKACINNETILMICIN
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AB894482

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aac(6')-Iak

aminoglycoside N-acetyltransferase AAC(6')-Iak

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

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Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic inactivation
Validation Method: plasmid transformation and MIC testing
Drug Classes: AMINOGLYCOSIDE, neomycin, netilmicin, sisomicin, tobramycin, AMIKACIN, DIBEKACIN
Organisms: Stenotrophomonas maltophilia AU12-09, Stenotrophomonas maltophilia, Stenotrophomonas maltophilia IOMTU250, Escherichia coli DH5α
Geographic Location: Nepal
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia AU12-09
Sequence Accession: APIT01000070.1
Protein Accession: EMI48985.1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: JVZQ01000186.1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: JZIW01000001.1
Protein Accession: KOO82158.1

PMID N/A

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: JZTX01000001.1
Protein Accession: KOO79896.1

Identification of a novel 6′-N-aminoglycoside acetyltransferase, AAC(6′)-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: 6′-N-aminoglycoside acetyltransferase
Source Database: Reslit
Confers Resistance To: neomycinnetilmicinsisomicintobramycin
Organisms Tested In: • Stenotrophomonas maltophilia IOMTU250
• Escherichia coli DH5α
Geographic Location: Nepal
Validation Method: plasmid transformation and MIC testing
Sequence Accession: AB894482

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AB894482.1
Protein Accession: BAO21229.1
Notes: ARO:3003199

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: AAC(6')-Iak
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Iak, AAC(6')
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: AMINOGLYCOSIDE
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AB894482.1
Protein Accession: BAO21229.1
Notes: ARO:3003199

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Research Article

PMID 25092711 · 2014

Gene Information

Gene Name: aac(6')-Iak
Allele: aac(6')-Iak
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: TOBRAMYCINAMIKACINSISOMICINDIBEKACINNETILMICIN
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AB894482

Comments (0)

No comments yet. Be the first to comment!

aac(6')-Iak

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aac(6')-Iak

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