Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside 6′-N-acetyltransferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| aac(6′)-Ib 11 | Reslit | 2 | amikacin, gentamicin | Salmonella enterica serovar Typhimurium +2 | - | 2003, 2010 | AY136758 | - |
| AAC(6')-Ib11 | Card DatabaseReference Gene CatalogResFinder Database | 5 | TOBRAMYCIN, AMIKACIN +3 | Salmonella enterica subsp. enterica serovar Typhimurium +1 | - | 2003, 2012 | AY136758.1 | AAN41403.1 |
Salmonella enterica Serovar Typhimurium bla PER-1 -Carrying Plasmid pSTI1 Encodes an Extended-Spectrum Aminoglycoside 6′- N -Acetyltransferase of Type Ib
Research Article
The study identifies a novel aac(6′)-Ib 11 gene encoding an extended-spectrum aminoglycoside 6′-N-acetyltransferase that confers resistance to amikacin and gentamicin. The gene was found to have unique amino acid substitutions at positions 118 and 119, leading to increased resistance levels.
Salmonella enterica serovar Typhimurium bla(PER-1)-carrying plasmid pSTI1 encodes an extended-spectrum aminoglycoside 6'-N-acetyltransferase of type Ib.
Research Article
Salmonella enterica serovar Typhimurium bla(PER-1)-carrying plasmid pSTI1 encodes an extended-spectrum aminoglycoside 6'-N-acetyltransferase of type Ib.
Research Article
Salmonella enterica serovar Typhimurium bla(PER-1)-carrying plasmid pSTI1 encodes an extended-spectrum aminoglycoside 6'-N-acetyltransferase of type Ib.
Research Article
Salmonella enterica serovar Typhimurium bla(PER-1)-carrying plasmid pSTI1 encodes an extended-spectrum aminoglycoside 6'-N-acetyltransferase of type Ib.
Research Article
Aminoglycoside modifying enzymes.
Review
The paper discusses various aminoglycoside modifying enzymes, particularly focusing on AAC(6')-Ib, AAC(6')-Ib-cr, and AAC(6')-Ib 11, which confer resistance to aminoglycosides like amikacin and gentamicin, and in some cases, quinolones.
qnr, aac(6')-Ib-cr and qepA genes in Escherichia coli and Klebsiella spp.: genetic environments and plasmid and chromosomal location.
Research Article
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