aac(6')-Im

aminoglycoside N-acetyltransferase AAC(6')-Im

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Enzymatic modification
Validation Method: cloning in E. coli DH5α and MIC testing
Drug Classes: TOBRAMYCIN, KANAMYCIN, AMIKACIN, gentamicin, tobramycin, amikacin, netilmicin, kanamycin a
Organisms: Escherichia coli, Enterococcus faecium, Campylobacter coli, [Clostridium] clostridioforme 90B1
Geographic Location: Slovakia|Belgium|Czech Republic|France|Guatemala|Mexico|Philippines|Portugal|South Africa|Thailand|Turkey|United States|Venezuela
Papers: 2
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers2

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Escherichia coli
Sequence Accession: AF337947.1
Protein Accession: AAK63041.1
Notes: ARO:3004629

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im, AAC(6')
Source Database: Card Database
Mechanism: Enzymatic modification, antibiotic inactivation
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Escherichia coli
Sequence Accession: AF337947.1
Protein Accession: AAK63041.1
Notes: ARO:3004629

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: Reference Gene Catalog
Mechanism: Enzymatic modification
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Escherichia coli
Sequence Accession: AGYO01000035.1
Protein Accession: ENZ04101.1
Notes: ARO:3004629

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: Reference Gene Catalog
Mechanism: Enzymatic modification
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Escherichia coli
Sequence Accession: AF337947.1
Protein Accession: AAK63041.1
Notes: ARO:3004629

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Escherichia coli
Sequence Accession: AF337947.1
Protein Accession: AAK63041.1
Notes: ARO:3004629

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im, AAC(6')
Source Database: Card Database
Mechanism: Enzymatic modification, antibiotic inactivation
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Escherichia coli
Sequence Accession: AF337947.1
Protein Accession: AAK63041.1
Notes: ARO:3004629

Aminoglycoside Resistance Genes aph(2")-Ib and aac(6′)-Im Detected Together in Strains of both Escherichia coli and Enterococcus faecium.

PMID 11557456 · 2001

The study identifies and characterizes the aminoglycoside resistance genes aph(2")-Ib and aac(6′)-Im, which confer resistance to various aminoglycoside antibiotics in both Escherichia coli and Enterococcus faecium.

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside acetyltransferase
Source Database: Reslit
Mechanism: acetylation of aminoglycosides
Confers Resistance To: gentamicintobramycinamikacinnetilmicinkanamycin a
Organisms Tested In: • Escherichia coli
• Enterococcus faecium
Geographic Location: Slovakia|Belgium|Czech Republic|France|Guatemala|Mexico|Philippines|Portugal|South Africa|Thailand|Turkey|United States|Venezuela
Validation Method: cloning in E. coli DH5α and MIC testing
Sequence Accession: AF337947

Whole-Genome Sequence of Multidrug-Resistant Campylobacter coli Strain COL B1-266, Isolated from the Colombian Poultry Chain.

PMID 26988047 · 2016

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: Reference Gene Catalog
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Campylobacter coli
Sequence Accession: LKIV02000117.1
Protein Accession: KWV61377.1

Whole-Genome Sequence of Multidrug-Resistant Campylobacter coli Strain COL B1-266, Isolated from the Colombian Poultry Chain.

PMID 26988047 · 2016

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: Reference Gene Catalog
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • Campylobacter coli
Sequence Accession: LKIV02000117.1
Protein Accession: KWV61377.1

PMID N/A

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: Reference Gene Catalog
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • [Clostridium] clostridioforme 90B1
Sequence Accession: AGYO01000035.1
Protein Accession: ENZ04101.1

PMID N/A

Gene Information

Gene Name: aac(6')-Im
Allele: AAC(6')-Im
Encodes: aminoglycoside N-acetyltransferase AAC(6')-Im
Source Database: Reference Gene Catalog
Confers Resistance To: TOBRAMYCINKANAMYCINAMIKACIN
Organisms Tested In: • [Clostridium] clostridioforme 90B1
Sequence Accession: AGYO01000035.1
Protein Accession: ENZ04101.1

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