aacc7

aminocyclitol 3-N-acetyltransferase

Validation StatusCandidate

Overview

Validation Method: cloning in Streptomyces plasmid pIJ702 and expression in Streptomyces lividans 1326
Drug Classes: Aminoglycoside
Organisms: Streptomyces rimosus forma paromomycinus, Streptomyces lividans 1326
Papers: 1
Databases: Reslit

Papers1

Isolation and nucleotide sequencing of an aminocyclitol acetyltransferase gene from Streptomyces rimosus forma paromomycinus.

PMID 2914849 · 1989

The aacC7 gene encoding an aminocyclitol 3-N-acetyltransferase was cloned and expressed in Streptomyces lividans 1326, demonstrating resistance to aminoglycosides.

Gene Information

Gene Name: aacc7
Allele: aacC7
Encodes: aminocyclitol 3-N-acetyltransferase
Source Database: Reslit
Confers Resistance To: Aminoglycoside
Organisms Tested In: • Streptomyces rimosus forma paromomycinus
• Streptomyces lividans 1326
Validation Method: cloning in Streptomyces plasmid pIJ702 and expression in Streptomyces lividans 1326
Sequence Accession: PMC209590

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