aadA5
ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Overview
- Drug Classes
- SPECTINOMYCIN, STREPTOMYCIN, streptomycin, spectinomycin
- Organisms
- Escherichia coli, Pseudomonas aeruginosa, uncultured bacterium +8 more
- Papers
- 10
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Mechanism
Enzymatic modification
Confers Resistance To
Organisms Tested In
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Mechanism
Enzymatic modification
Confers Resistance To
Organisms Tested In
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Mechanism
Enzymatic modification
Confers Resistance To
Organisms Tested In
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Mechanism
Enzymatic modification
Confers Resistance To
Organisms Tested In
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Mechanism
Enzymatic modification
Confers Resistance To
Organisms Tested In
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Mechanism
Enzymatic modification
Confers Resistance To
Organisms Tested In
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.
PMID 10582907 · 1999The study identifies a novel streptomycin and spectinomycin resistance gene, aadA5, located within a class 1 integron in a pathogenic porcine E. coli isolate. The gene was successfully cloned and shown to confer resistance to streptomycin and spectinomycin.
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- adenylylation enzyme that modifies streptomycin and spectinomycin
- Validation Method
- cloning in E. coli + MIC testing
Confers Resistance To
Organisms Tested In
Isolation Details
Mechanisms of resistance in multiple-antibiotic-resistant Escherichia coli strains of human, animal, and food origins.
PMID 15388464 · 2004Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- aminoglycoside adenyltransferase
- Validation Method
- PCR and sequencing
Confers Resistance To
Organisms Tested In
The IncP-6 plasmid Rms149 consists of a small mobilizable backbone with multiple large insertions.
PMID 15995187 · 2005The study characterizes the IncP-6 plasmid Rms149, identifying several AMR genes including aac(3)-I, aadA5, intI1, qacEΔ1, and sul1, which confer resistance to gentamicin, streptomycin, spectinomycin, quaternary ammonium compounds, and sulfonamide, respectively.
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- streptomycin and spectinomycin resistance
- Validation Method
- cloning and functional analysis
Confers Resistance To
Organisms Tested In
Plasmid pB8 is closely related to the prototype IncP-1beta plasmid R751 but transfers poorly to Escherichia coli and carries a new transposon encoding a small multidrug resistance efflux protein.
PMID 16122561 · 2005Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Plasmid pB8 is closely related to the prototype IncP-1beta plasmid R751 but transfers poorly to Escherichia coli and carries a new transposon encoding a small multidrug resistance efflux protein.
PMID 16122561 · 2005Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study.
PMID 18550679 · 2008Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study.
PMID 18550679 · 2008Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study.
PMID 18550679 · 2008Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study.
PMID 18550679 · 2008Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Evidence for dynamic exchange of qac gene cassettes between class 1 integrons and other integrons in freshwater biofilms.
PMID 19459951 · 2009Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Evidence for dynamic exchange of qac gene cassettes between class 1 integrons and other integrons in freshwater biofilms.
PMID 19459951 · 2009Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Occurrence of integron-associated resistance gene cassettes located on antibiotic resistance plasmids isolated from a wastewater treatment plant.
PMID 19719593 · 2003Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Occurrence of integron-associated resistance gene cassettes located on antibiotic resistance plasmids isolated from a wastewater treatment plant.
PMID 19719593 · 2003Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City.
PMID 20667885 · 2010Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City.
PMID 20667885 · 2010Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Discovery and characterization of gene cassettes-containing integrons in clinical strains of Riemerella anatipestifer.
PMID 22112855 · 2012Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Discovery and characterization of gene cassettes-containing integrons in clinical strains of Riemerella anatipestifer.
PMID 22112855 · 2012Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
New integron gene arrays from multiresistant clinical isolates of members of the Enterobacteriaceae and Pseudomonas aeruginosa from hospitals in Malaysia.
PMID 23180481 · 2013Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
New integron gene arrays from multiresistant clinical isolates of members of the Enterobacteriaceae and Pseudomonas aeruginosa from hospitals in Malaysia.
PMID 23180481 · 2013Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
Gene Information
- Gene Name
- aadA5
- Allele
- AadA5
- Encodes
- ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5
Confers Resistance To
Organisms Tested In
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