The study characterizes In53, a unique class 1 integron in Escherichia coli that carries multiple antibiotic resistance gene cassettes, including aadB, arr-2, cmlA5, qacI, aacA1b/orfG, oxa10, and aadA1, each contributing to resistance against various antibiotics.

The study identifies genetic markers of extensive drug-resistant Pseudomonas aeruginosa high-risk clones, including ampC hyperproduction, oprD inactivation, aadB gene production, and mexZ mutations, along with specific mutations in ampR, gyrA, and parC that contribute to resistance.

The study identified multiple antimicrobial resistance genes in plasmids from multidrug-resistant Salmonella enterica serotype Heidelberg isolates, including bla CMY, aadA, aadB, aphA, strA, strB, sul1, sul2, tetA, floR, cmlA, dfrA1, dfrA12, and aacC.

The study reports the first identification of NDM-1-producing Acinetobacter baumannii in East Africa, highlighting the presence of various resistance genes including bla(NDM-1), bla(OXA-23), bla(OXA-51-like), bla(ADC), armA, aadB, aac(6')-Ib, and aph(3')-VI.

The study identified multiple antimicrobial resistance genes in Acinetobacter baumannii isolates from military treatment facilities, including bla OXA-51-like, bla OXA-23, bla GES-11, aac(6')-Ib, aacC1, aadB, aphA6, and others, highlighting the complex resistome of these isolates.

The study identified several AMR genes and mutations in Salmonella enterica serotype Heidelberg isolates, including bla, aac(6')-Ib, tet(M), qnrS1, and erm(B). Mutations in genes such as SEEHRA37_03221, SEEHRA37_24108, and others were associated with resistance traits.

The study identified the aadB gene on plasmid pRAY*-v3, which confers resistance to aminoglycosides such as gentamicin, streptomycin, and kanamycin. Additionally, the plasmid pAB49-v1 was characterized, although it did not show clear resistance mechanisms.

The study identified various aminoglycoside resistance genes and novel transposons, including Tn6279, ΔTn6279, and Tn1548-like structures, contributing to the resistance of carbapenem-resistant Acinetobacter baumannii isolates.

The study identified a bla ROB-1 gene in an integrative conjugative element (ICE) of M. haemolytica, which had a single nucleotide substitution leading to a non-functional gene and sensitivity to ampicillin.

The study identified aac(6')-Ib, aphA1, and aadB as the most frequently detected aminoglycoside resistance genes in Pseudomonas aeruginosa isolates from HUAPA, Cumana, Venezuela. These genes were associated with resistance to tobramycin and amikacin.

The study presents a real-time analysis framework for MinION sequencing data, demonstrating the ability to identify pathogens and antibiotic resistance genes within a few hours of sequencing. Key resistance genes identified include blaSHV, mphA, strA, strB, blaTEM, sul2, blaOXA, aac3, aac6, blaCMY, blaCFE, blaLAT, blaBIL, QnrB, aadA, oqxA, tetA, oqxB, rmtC, sul1, sul3, fosA, blaNDM, oqxA, blaSHV, oqxB, aadB, sul1, sul3, blaOXA, blaOKP, fosA, blaSHV, blaOKP, blaLEN, oqxA, and oqxB.

The study identifies the bla NDM-1 gene as a major cause of carbapenem resistance in Vibrio fluvialis isolates from Kolkata, India. Several additional resistance genes, including aadA1, aadB, aac(6')-Ib-cr, sul1, sul3, floR, bla OXA-1, bla OXA-7, bla OXA-9, bla TEM-9, bla CTX-M-3, strA, and tetB, were also characterized.

The study identified multiple AMR genes and mutations contributing to multidrug resistance in Pseudomonas aeruginosa ST175, including aadB and aadA13 for aminoglycoside resistance, ampR and oprD mutations for β-lactam resistance, mexZ for efflux pump overexpression, and gyrA, parC, and glpT mutations for fluoroquinolone and fosfomycin resistance.

The study identifies carbapenem-resistant Acinetobacter indicus-like isolates from cattle carrying the blaOXA-23 gene, along with various other AMR genes such as aac(3)-IIa, strA/B, aph(3')-Ic, sul2, floR, tet(A), tet(Y), aadA1, aadB, sul1, and tet(X).

The study identified several antibiotic resistance genes in E. coli isolates from diarrheic buffalo calves in Egypt, including aadB, blaTEM, and Sul1, which confer resistance to aminoglycosides, beta-lactams, and sulfonamides, respectively.

The study identified various AMR genes and mutations in extensively drug-resistant Pseudomonas aeruginosa isolates from Spain, including beta-lactamases, aminoglycoside-modifying enzymes, and mutations in genes such as ampC, oprD, gyrA, parC, mexZ, and glpT, which contribute to resistance against multiple antibiotics.

The study identified 18 antibiotic resistance genes in the multidrug-resistant Acinetobacter baumannii DMS06669 strain, including eight novel genes not previously reported in A. baumannii. These genes conferred resistance to various antibiotic classes, including aminoglycosides, beta-lactams, phenicols, sulfonamides, tetracyclines, macrolides, lincosamides, streptogramin B, and rifampicins.

The study identifies the aadB gene on small mobilizable plasmids (SMPs) as a contributor to aminoglycoside resistance in Acinetobacter baumannii, highlighting the role of plasmids in the dissemination of multidrug resistance.

The study identified genes under positive selection in Pseudomonas aeruginosa outlier strains, including oprD, which is implicated in carbapenem resistance through reduced uptake.

The study developed and validated 85 PCR assays to detect 79 AMR genes and mutations associated with resistance across 10 antimicrobial classes, focusing on E. coli. The assays showed high concordance with sequencing and phenotypic susceptibility testing, demonstrating their potential for AMR surveillance in E. coli isolates and direct stool specimens.

The study identifies a multidrug-resistant E. coli strain carrying both mcr-1 and bla NDM-1, highlighting the co-existence of colistin and carbapenem resistance genes in Vietnam.

The study identifies several AMR genes in multidrug-resistant Gram-negative bacteria isolated from German surface waters, highlighting the presence of clinically relevant resistance mechanisms such as bla CTX-M-1, bla CTX-M-15, mcr-1, and others.

The study identified 24 different antimicrobial-resistance determinants in Gallibacterium anatis isolates from calves with unresponsive bronchopneumonia, including novel resistance genes such as aadA23, blaCARB-8, tet(Y), and qnrD1.

The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.

The study reports the first autochthonous extensively drug-resistant NDM-1 Pseudomonas aeruginosa ST235 strain in Italy, highlighting the presence of multiple beta-lactamase genes, aminoglycoside modifying enzymes, and multidrug efflux pumps contributing to its extensive drug resistance.

The study identified aadB, sul1, and bla-TEM as the primary antimicrobial resistance genes in E. coli isolates from diarrheic calves, with aadB being the most prevalent.

The study identifies various antibiotic resistance genes in commensal E. coli isolates, highlighting the prevalence of resistance genes on F plasmids and the role of mobile genetic elements in their dissemination.

The study shows that removing the AbaR resistance island from Acinetobacter baumannii restores antibiotic susceptibility and increases natural transformability. Several AMR genes within AbaR were identified, including aadB, aacC1, aphA1b, aacA, aadA1, strA, strB, blaVEB-1, blaOXA-10, sul1, dhfrI, dhfrX, tetA(A), tetA(G), cmlA1, cmlA5, cmlA9, catA1, arr-2, and sup.

The study identified diverse gene cassette arrays in commensal E. coli from intensive farming swine in four Chinese provinces, highlighting the prevalence of multidrug resistance mediated by class 1 integrons and specific gene cassettes.

The study identified several AMR genes and mutations in ESKAPEE pathogens, including vanA, vanB, blaTEM, blaSHV, blaCTX-M, blaOXA, blaVEB, blaVIM, blaNDM, aac(6')-Ib, aadB, ermC, qnrS1, and gyrA mutations, highlighting the prevalence of multidrug resistance in these isolates.

The study identified various antibiotic resistance genes (ARGs) in river biofilms upstream and downstream of a wastewater treatment plant (WWTP), including qnrA, qnrS, mfsA, ermC, ermX, macB, mefA_10, cat, catB3, aadB, aph(3')-III, AAC(3)-Ib, bacA_1, blaPer-1, blaIMP, blaTEM, blaKPC, blaDHA, cblA, ermC, ermY, ermX, mdtL, cusF, copD, qacA, mecA, dfrF, arnA, sul1, sulA, vat(A), IS6100, ISS1N, Intl1, blaCTX-M, blaIMP, mefA_10, tolC, mdfF, acrA, dfrA27, aac(6')-IIa, vanA, intl3, and TTV. These genes were associated with resistance to various antibiotics such as fluoroquinolones, macrolides, chloramphenicol, aminoglycosides, beta-lactams, polymyxins, sulfonamides, and others. The study also found that the resistome composition varied between upstream and downstream sites, indicating the impact of WWTP effluents on the distribution of ARGs in river biofilms.

The study identified various AMR genes in Acinetobacter spp. isolated from pet reptiles, including tetracycline, sulfonamide, and aminoglycoside resistance genes, highlighting the presence of multidrug-resistant strains in these animals.

The study identifies multiple antibiotic resistance genes, including bla OXA-58, bla NDM-1, ble MBL, sul2, aacC2d, msr(E)-mph(E), and tet(B), in GR13-type plasmids from Acinetobacter isolates, highlighting their role in multidrug resistance and horizontal gene transfer.

The study characterizes the bla NDM-5 gene in multidrug-resistant commensal E. coli from diarrheal patients, highlighting its resistance to various antibiotics and its potential for horizontal transfer.

The study identifies novel antibiotic resistance genes, including blaVEB-1, tetA(E), and mcr-3.15, in clinical isolates of Aeromonas, highlighting the presence of chromosome-borne accessory genetic elements and new resistance mechanisms.

The study identified several antibiotic resistance genes (ARGs) in wastewater treatment plants (WWTPs) in cold environments, highlighting their role as hotspots for the dissemination of ARGs. Key genes included aadA, aadB, ampC, blaSHV, blaTEM, dfrA1, ermB, fosA, qnrS, and tetA(A).

The study presents eleven novel primer sets for the detection and quantification of antibiotic resistance genes (ARGs) in environmental samples using qPCR. These primers target genes such as aadA, aadB, ampC, blaTEM, blaSHV, dfrA1, ermB, fosA, mecA, qnrS, and tetA(A), which are responsible for resistance to various antibiotics including aminoglycosides, beta-lactams, trimethoprim, macrolides, fosfomycin, quinolones, and tetracyclines.

The study characterizes the global genomic epidemiology of blaGES-5, a carbapenemase-associated integron, highlighting its prevalence in Pseudomonas aeruginosa and its association with various gene cassettes.

The study identified BlaTEM, aadB, and Sul1 as the resistance genes in E. coli isolates from bovine mastitis cases, with all isolates showing resistance to gentamycin, ampicillin, cefquinome, cefixime, and sulfamethoxazole-trimethoprim.

The study identifies various acquired antibiotic resistance genes in Pseudomonas spp., Escherichia coli, and Acinetobacter spp. in the Western Balkans and Hungary, including beta-lactamases like bla VIM-2-like, bla NDM-1, bla OXA-23, and bla OXA-66, aminoglycoside resistance genes such as aacA4, aadA2, and aphA, sulfonamide resistance gene sul1, and others. These genes confer resistance to multiple antibiotics, highlighting the complexity of antimicrobial resistance in the region.

The study identifies the emergence of carbapenem-resistant Acinetobacter baumannii clonal complex 2 (CC2) in multiple hospitals in São Paulo, Brazil, with resistance genes including blaOXA-23, armA, aadB, aphA1, aphA6, sul1, sul2, and tetB.

The study identifies various AMR genes and mutations in Pseudomonas paraeruginosa, including carbapenemases like blaVIM-2, blaVIM-6, blaVIM-28, and blaKPC-2, as well as efflux pump genes (mexAB-oprM, mexCD-oprJ, etc.), and mutations in oprD, mexS, mexR, mexZ, lasR, mvfR, and vqsM that contribute to antibiotic resistance.