aada1a

aminoglycoside adenyltransferase

Validation StatusCandidate

Overview

Mechanism: adenylation
Validation Method: PCR and sequencing
Drug Classes: streptomycin, spectinomycin
Organisms: Escherichia coli, Acinetobacter baumannii
Geographic Location: Italy
Papers: 2
Databases: Reslit

Papers2

A multiresistant clone of Shiga toxin-producing Escherichia coli O118:[H16] is spread in cattle and humans over different European countries.

PMID 12450802 · 2002

Gene Information

Gene Name: aada1a
Allele: aadA1a
Encodes: aminoglycoside adenyltransferase
Source Database: Reslit
Confers Resistance To: streptomycin
Organisms Tested In: • Escherichia coli
Validation Method: PCR and sequencing

Molecular epidemiology of sequential outbreaks of Acinetobacter baumannii in an intensive care unit shows the emergence of carbapenem resistance.

PMID 15004037 · 2004

The study identifies several AMR genes, including aacC1, aadA1a, aacA4, blaOXA-20, and blaIMP, which confer resistance to various antibiotics in carbapenem-resistant Acinetobacter baumannii strains.

Gene Information

Gene Name: aada1a
Allele: aadA1a
Encodes: AAD(3")-Ia aminoglycoside adenyltransferase
Source Database: Reslit
Mechanism: adenylation
Confers Resistance To: spectinomycinstreptomycin
Organisms Tested In: • Acinetobacter baumannii
Geographic Location: Italy
Validation Method: gene characterization
Sequence Accession: AY307113|AY307114

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aada1a

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