acrAB

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	G123A	-	Escherichia coli, Pseudomonas aeruginosa, E. coli	Fluoroquinolones\|Glycylcyclines\|Macrolide\|Aminoglycoside	Reslit	Candidate

Papers2

Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides.

Mutations in the promoter region of acrAB were associated with decreased tachyplesin accumulation.

Environmental complexity is more important than mutation in driving the evolution of latent novel traits in E. coli.

Mutations in the promoter region of acrAB were observed in clones evolved in complex environments.

Nucleotide Change: G123A
Organisms: E. coli
Confers Resistance To: Fluoroquinolones|Glycylcyclines|Macrolide|Aminoglycoside
Source Database: Reslit