amgrs

two-component regulator

Validation StatusCandidate

Overview

Mechanism: regulates an adaptive response to membrane stress
Validation Method: mutant screening and complementation analysis
Drug Classes: Aminoglycoside
Organisms: Pseudomonas aeruginosa
Papers: 1
Databases: Reslit

Papers1

Targeting a bacterial stress response to enhance antibiotic action.

PMID 19706543 · 2009

The study identifies the two-component regulator AmgRS as a potential target to enhance aminoglycoside efficacy against Pseudomonas aeruginosa by increasing antibiotic sensitivity.

Gene Information

Gene Name: amgrs
Allele: amgRS
Encodes: two-component regulator
Source Database: Reslit
Mechanism: regulates an adaptive response to membrane stress
Confers Resistance To: Aminoglycoside
Organisms Tested In: • Pseudomonas aeruginosa
Validation Method: mutant screening and complementation analysis

Comments (0)

No comments yet. Be the first to comment!

Browse AMR Genes

amgrs

Gene Information