ant(3'')-Ii-aac(6')-IId

aminoglycoside resistance protein

Validation StatusCandidate

Overview

Mechanism: bifunctional ANT(3")-I and AAC(6′)-II
Validation Method: cloning in E. coli + disk diffusion
Drug Classes: streptomycin, spectinomycin
Organisms: Serratia marcescens, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion.

PMID 11959575 · 2002

The study identifies a novel aminoglycoside resistance gene fusion, ant(3")-Ii-aac(6′)-IId, which confers resistance to streptomycin, spectinomycin, and gentamicin. This gene is part of a class I integron and is associated with a group II intron.

Gene Information

Gene Name: ant(3'')-Ii-aac(6')-IId
Allele: ant(3'')-Ii-aac(6')-IId
Encodes: aminoglycoside resistance protein
Source Database: Reslit
Mechanism: bifunctional ANT(3")-I and AAC(6′)-II
Confers Resistance To: streptomycinspectinomycin
Organisms Tested In: • Serratia marcescens
• Escherichia coli
Validation Method: cloning in E. coli + disk diffusion
Sequence Accession: AF453998|AF453999

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ant(3'')-Ii-aac(6')-IId

Gene Information