ResLit

aph(2'')-If

aminoglycoside O-phosphotransferase APH(2'')-If, APH(2'')

NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to aph(2'')-If
AMR Rules
Browse AMR rules for aph(2'')-If
Curation StatusNot Validated

Overview

Drug Classes
TOBRAMYCIN, KANAMYCIN, AMIKACIN, GENTAMICIN
Organisms
Campylobacter jejuni, Campylobacter coli
Papers
1
Papers1
1

Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen.

PMID 23129050 · 2013

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If, APH(2'')

Mechanism

Enzymatic modification, antibiotic inactivation

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter jejuni
2

Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen.

PMID 23129050 · 2013

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter jejuni
3

Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen.

PMID 23129050 · 2013

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter jejuni
4

Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen.

PMID 23129050 · 2013

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter jejuni
5

Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen.

PMID 23129050 · 2013

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If, APH(2'')

Mechanism

Enzymatic modification, antibiotic inactivation

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter jejuni
6

Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen.

PMID 23129050 · 2013

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter jejuni
7
PMID N/A

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter coli
8
PMID N/A

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter coli
9
PMID N/A

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter coli
10
PMID N/A

Gene Information

Gene Name
aph(2'')-If
Allele
APH(2'')-If
Encodes
aminoglycoside O-phosphotransferase APH(2'')-If

Mechanism

Enzymatic modification

Confers Resistance To

TOBRAMYCINKANAMYCINAMIKACINGENTAMICIN

Organisms Tested In

• Campylobacter coli
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