Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside O-phosphotransferase APH(6)-Ia
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| APH(6)-Ia | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | STREPTOMYCIN, Gentamicin +2 | Streptomyces griseus +1 | Europe|Asia|North America|South America|Brazil |
| 1987, 2022 |
| Y00459.1 |
| CAA68516.1 |
| aph(6')-I | Reslit | 1 | Aminoglycoside | Klebsiella pneumoniae | Europe | 2021 | CP062225|CP062226|CP062227|CP062228|CP062229|CP062230|CP062231|CP062232|CP062233|CP062234|CP062235|CP062236 | - |
| APH(6)-I | Reslit | 1 | Aminoglycoside | Klebsiella pneumoniae | Portugal | 2022 | - | - |
| aph(6)-Ia | ResFinder Database | 1 | STREPTOMYCIN, KANAMYCIN, STREPTOMYCIN | Streptomyces griseus | - | - | AY971801, Y00459 | - |
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity.
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity.
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity.
Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare.
The study reports an outbreak of NDM-1-producing Klebsiella pneumoniae in an ICU during the COVID-19 pandemic, highlighting the presence of multiple AMR genes including blaNDM-1, blaTEM-1, blaCTX-M-15, blaOXA-1, blaCMY-4, and others, along with mutations in ParC and GyrA contributing to quinolone resistance.
Genomic epidemiological analysis of Klebsiella pneumoniae from Portuguese hospitals reveals insights into circulating antimicrobial resistance.
The study identifies bla KPC-3 and bla CTX-M-15 as the primary carbapenem and extended-spectrum beta-lactamase resistance genes, respectively, in Klebsiella pneumoniae isolates from Portugal. Other notable AMR genes include aac(6')-Ib-cr, qnrB, aac(3)-II, APH(3')-I, ANT(3'')-I, and APH(6)-I, which contribute to resistance against fluoroquinolones and aminoglycosides.
How Streptococcus suis escapes antibiotic treatments.
The study characterizes various AMR genes and mutations in Streptococcus suis, highlighting resistance to beta-lactams, macrolides, lincosamides, streptogramins, amphenicols, pleuromutilins, tetracyclines, sulfonamides, trimethoprim, and fluoroquinolones.
Extensive screening reveals previously undiscovered aminoglycoside resistance genes in human pathogens.
The study identifies numerous novel aminoglycoside resistance genes (AMEs) in human pathogens through extensive computational screening of bacterial genomes. Twenty-four out of twenty-eight experimentally tested AMEs conferred resistance to aminoglycosides in E. coli, with seventeen exceeding clinical breakpoints.
Unde venis? Bacterial resistance from environmental reservoirs to lettuce: tracking microbiome and resistome over a growth period.
The study identified multidrug and β-lactam antibiotic resistance genes (ARGs) in lettuce and water, while lettuce and soil uniquely shared mainly glycopeptide and tetracycline ARGs. Manure was found to be the main source of resistance markers on young lettuce plants.
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