Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside 3'-phosphotransferase
Overview
The genome of Streptococcus mitis B6--what is a commensal?
The study identifies multiple antibiotic resistance genes in Streptococcus mitis B6, including tetM, aacA-aphD, aphA, sat, and aadE, which confer resistance to tetracycline and aminoglycosides. Additionally, a mutation in rpoB (H486N) was found to confer rifampicin resistance.
Characterization of a Streptococcus suis tet(O/W/32/O)-carrying element transferable to major streptococcal pathogens.
The study identifies a novel mobile genetic element, 15K, carrying multiple antibiotic resistance genes including tet(O/W/32/O), erm(B), aadE, aphA, and tet(40), which can be transferred between major streptococcal pathogens.
DNA sequence analysis of plasmids from multidrug resistant Salmonella enterica serotype Heidelberg isolates.
The study identified multiple antimicrobial resistance genes in plasmids from multidrug-resistant Salmonella enterica serotype Heidelberg isolates, including bla CMY, aadA, aadB, aphA, strA, strB, sul1, sul2, tetA, floR, cmlA, dfrA1, dfrA12, and aacC.
Enhanced horizontal transfer of antibiotic resistance genes in freshwater microcosms induced by an ionic liquid.
The ionic liquid [BMIm][PF6] enhances the horizontal transfer of antibiotic resistance genes (ARGs) mediated by plasmid RP4 in freshwater microcosms, leading to increased resistance to ampicillin, kanamycin, and tetracycline.
The horizontal transfer of antibiotic resistance genes is enhanced by ionic liquid with different structure of varying alkyl chain length.
The study shows that ionic liquids (ILs) enhance the horizontal transfer of antibiotic resistance genes (ARGs) via plasmid RP4, particularly the aphA and traF genes, in aquatic environments. The effectiveness decreases with longer alkyl chains in the ILs.
Genomic Analysis Reveals Multi-Drug Resistance Clusters in Group B Streptococcus CC17 Hypervirulent Isolates Causing Neonatal Invasive Disease in Southern Mainland China.
The study identifies multiple antibiotic resistance genes, including tetO, ermB, ant6, aphA, ant9, and lnuB, in Group B Streptococcus CC17 isolates from China, highlighting the emergence of multi-drug resistance in these hypervirulent strains.
Virulence and Genomic Feature of Multidrug Resistant Campylobacter jejuni Isolated from Broiler Chicken.
The study identified multiple AMR genes and mutations in Campylobacter jejuni 1655, including gyrA T86I mutation, 23S rRNA A2075G mutation, tetO, aphA, and aadE genes, contributing to resistance against fluoroquinolones, macrolides, tetracycline, and aminoglycosides.
ICESag37, a Novel Integrative and Conjugative Element Carrying Antimicrobial Resistance Genes and Potential Virulence Factors in Streptococcus agalactiae.
The study characterizes ICE Sag37, a novel integrative and conjugative element carrying multiple antimicrobial resistance genes, including erm(B), tet(O), aadE, aphA, and ant(6), in Streptococcus agalactiae.
Molecular cloning and analysis of Staphylococcus aureus chromosomal aminoglycoside resistance genes.
The study identified and characterized the chromosomal aminoglycoside resistance genes aphA and aacA in Staphylococcus aureus, which confer resistance to kanamycin, neomycin, and streptomycin. These genes were cloned and expressed in E. coli and B. subtilis, demonstrating their functionality.
Characterization of a new transferable MDR plasmid carrying the pbp5 gene from a clade B commensal Enterococcus faecium.
Bloodstream and catheter-related infections due to different clones of multidrug-resistant and biofilm producer Corynebacterium striatum.
The study identified multiple AMR genes (ermX, aphA, cmx) and mutations in the gyrA gene associated with fluoroquinolone resistance in multidrug-resistant Corynebacterium striatum isolates.
Characterization of Enterococci- and ESBL-Producing Escherichia coli Isolated from Milk of Bovides with Mastitis in Egypt.
The study identified several AMR genes in Enterococcus and ESBL-producing E. coli isolates from bovine mastitis cases in Egypt, including erm(B), tetL, aac-aphD, vanA, and vanB.
Antibiotic Resistance and Phylogeny of Pseudomonas spp. Isolated over Three Decades from Chicken Meat in the Norwegian Food Chain.
The study identified several AMR genes and mutations in Pseudomonas spp. isolated from chicken meat in Norway, including beta-lactamases, efflux pumps, and genes involved in resistance to aminoglycosides, fluoroquinolones, and colistin.
Antimicrobial Resistance Genes in ESBL-Producing Escherichia coli Isolates from Animals in Greece.
The study identified several AMR genes in ESBL-producing E. coli isolates from animals in Greece, including bla CTX-M-1/15, bla TEM, aadA1, aadA2, aphA, strA, strB, sul1, sul2, sul3, dfrA1, dfrA5, dfrA7, dfrA12, dfrA14, dfrA15, dfrA17, dfrA19, mph, mrx, intI1, tnpISE cp1, qnrS, and qnrB.
Biological Mitigation of Antibiotic Resistance Gene Dissemination by Antioxidant-Producing Microorganisms in Activated Sludge Systems.
The study demonstrates that antioxidant-producing microorganisms, such as Deinococcus radiodurans R1 and Rhodotorula sp., can mitigate the dissemination of antibiotic resistance genes (ARGs) in activated sludge systems by reducing the persistence of plasmid RP4 and the enrichment of sul1 and intl1. These microorganisms also decrease the diversity of ARG hosts and limit the conjugative transfer of ARGs.
Plethora of Resistance Genes in Carbapenem-Resistant Gram-Negative Bacteria in Greece: No End to a Continuous Genetic Evolution.
The study identified a variety of resistance genes in carbapenem-resistant Gram-negative bacteria, including bla KPC, bla NDM, bla VIM, and others, highlighting the complex genetic diversity of these pathogens.
Cross-Sectional Survey of Antibiotic Resistance in Extended Spectrum β-Lactamase-Producing Enterobacteriaceae Isolated from Pigs in Greece.
The study identified a high prevalence of ESBL-producing Enterobacteriaceae in Greek pigs, with a focus on resistance mechanisms involving bla CTX-M1/15, bla TEM, and bla SHV genes, as well as resistance to fluoroquinolones, aminoglycosides, sulfonamides, trimethoprim, macrolides, and colistin.
Comparative genomics analysis of the multidrug-resistant Aeromonas hydrophila MX16A providing insights into antibiotic resistance genes.
The study identified multiple antibiotic resistance genes in Aeromonas hydrophila MX16A, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline efflux pumps, and quinolone resistance determinants, contributing to its multidrug-resistant phenotype.
Clonal Complex 12 Serotype Ib Streptococcus agalactiae Strain Causing Complicated Sepsis in Neonates: Clinical Features and Genetic Characteristics.
The study identifies the presence of the integrative and conjugative element ICE Sag37 in type Ib ST12 GBS isolates, which carries multiple antibiotic resistance genes such as erm(B), tet(O), aadE, aphA, ant-6, lsa(E), and lun(B), contributing to high resistance rates to erythromycin and clindamycin. Additionally, the virulence gene pezT was found in these isolates.
Reduced selection for antibiotic resistance in community context is maintained despite pressure by additional antibiotics.
The study characterizes the resistance genes aacC1, aphA, and aadA, which confer resistance to gentamicin, kanamycin, and streptomycin, respectively, in Escherichia coli MG1655. These genes were experimentally validated through chromosomal tagging and electroporation techniques.
Detecting patterns of accessory genome coevolution in Staphylococcus aureus using data from thousands of genomes.
The study identifies coevolving genes in Staphylococcus aureus, highlighting interactions among antibiotic resistance genes, mobile genetic elements, and virulence factors. Key findings include the coevolution of beta-lactam resistance genes (blaZ, blaI, blaR1), metal resistance genes (cadA, cadC, copB, mco), and plasmid replication genes (repD, repE, repN, pre).
Identification, characterization, and distribution of novel amidase gene aphA in sphingomonads conferring resistance to amphenicol antibiotics.
The study identifies and characterizes the novel amidase gene aphA from Sphingobium yanoikuyae B1, which confers resistance to amphenicol antibiotics by hydrolyzing the amide bond, leading to the inactivation of chloramphenicol, thiamphenicol, and florfenicol.
Characterizing Methicillin-Resistant Staphylococcus spp. and Extended-Spectrum Cephalosporin-Resistant Escherichia coli in Cattle.
The study identified several AMR genes in E. coli and MRSA isolates from cattle in Austria, including bla CTX-M-1/15, bla CTX-M-9, bla TEM, tet (A), tet (B), dfrA1, dfrA5, dfrA14, dfrA17, sul2, sul3, aadA1, aadA2, floR, cmlA, aphA, and bla ACT. Additionally, the MRSA isolate carried the mecA gene, indicating methicillin resistance.
Acquired antibiotic resistance of Pseudomonas spp., Escherichia coli and Acinetobacter spp. in the Western Balkans and Hungary with a One Health outlook.
The study identifies various acquired antibiotic resistance genes in Pseudomonas spp., Escherichia coli, and Acinetobacter spp. in the Western Balkans and Hungary, including beta-lactamases like bla VIM-2-like, bla NDM-1, bla OXA-23, and bla OXA-66, aminoglycoside resistance genes such as aacA4, aadA2, and aphA, sulfonamide resistance gene sul1, and others. These genes confer resistance to multiple antibiotics, highlighting the complexity of antimicrobial resistance in the region.
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