Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Aminoglycoside phosphotransferase
Overview
Microarray-based characterisation of a Panton-Valentine leukocidin-positive community-acquired strain of methicillin-resistant Staphylococcus aureus
The study identified the presence of the tetK and far1 genes in a Panton-Valentine leukocidin-positive community-acquired methicillin-resistant Staphylococcus aureus strain, which conferred resistance to tetracycline and fusidic acid respectively. A novel plasmid (pUB102) carrying these genes was also characterized.
A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus.
The study characterizes various methicillin-resistant Staphylococcus aureus (MRSA) clones, highlighting their antimicrobial resistance and virulence-associated markers, with a focus on SCC mec types and PVL status.
Identification of a novel gene product that promotes survival of Mycobacterium smegmatis in macrophages.
The study identifies MSMEG_5817 as a gene involved in the intracellular survival of Mycobacterium smegmatis within macrophages. Disruption of MSMEG_5817 leads to reduced intracellular survival, and complementation restores survival to wild-type levels.
DNA microarray profiling of a diverse collection of nosocomial methicillin-resistant staphylococcus aureus isolates assigns the majority to the correct sequence type and staphylococcal cassette chromosome mec (SCCmec) type and results in the subsequent identification and characterization of novel SCCmec-SCCM1 composite islands.
The study identifies and characterizes novel SCCmec-SCCM1 composite islands in MRSA isolates, highlighting the presence of various AMR genes such as blaZ, erm(A), aadD, qacA, qacC, merA, merB, fosB, sdrM, aacA-aphD, far1 (fusB), Q6GD50 (fusC), and cat-pC194 (pMC524).
Genotypic resistance testing creates new treatment challenges: two cases of oxacillin-susceptible methicillin-resistant Staphylococcus aureus.
Two cases of oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA) were identified, highlighting the importance of genotypic testing for accurate detection of mecA-positive strains despite phenotypic susceptibility to oxacillin.
Epidemiology and molecular characterization of methicillin-resistant Staphylococcus aureus nasal carriage isolates from bovines.
The study identified multiple AMR genes in MRSA isolates from bovines, including blaZ, blaI, blaR, tetM, ermC, aacA-aphD, aadD, aphA3, cat, sdrM, and fosB, which confer resistance to penicillin, tetracycline, erythromycin, gentamicin, kanamycin, chloramphenicol, and fosfomycin.
Characterization of mannitol-fermenting methicillin-resistant staphylococci isolated from pigs in Nigeria.
The study identified multiple antimicrobial resistance genes in methicillin-resistant staphylococci isolated from pigs in Nigeria, including mecA, blaZ, erm(C), erm(B), str, tet(K), tet(M), tet(L), dfrG, dfrK, aacA/aphD, aphA3, cat pC221, and cat pC223. Additionally, a Ser84Leu mutation in the gyrA gene was found to confer ciprofloxacin resistance.
Identification of Genes Coding Aminoglycoside Modifying Enzymes in E. coli of UTI Patients in India.
The study identifies the presence of aminoglycoside modifying enzyme genes rrs, aacC2, aacA-aphD, and aphA3 in E. coli isolates from UTI patients in India, indicating a mechanism of resistance to aminoglycoside antibiotics.
Shifts in the Clonal Distribution of Methicillin-Resistant Staphylococcus aureus in Kuwait Hospitals: 1992-2010.
The study identified various AMR genes in MRSA isolates from Kuwait hospitals, including aphA3, aacA-aphD, ermA, ermC, mupA, tetK, tetM, fusC, far1, msrA, mphC, sat, qacA, qacC, merA, merB, dfrS1, aadD, fosB, cat, sdrM, icaA, icaC, and icaD, which conferred resistance to multiple antibiotics.
Variety of Antimicrobial Resistances and Virulence Factors in Staphylococcus aureus Isolates from Meat Products Legally and Illegally Introduced to Germany.
The study identified multiple antimicrobial resistance genes and mutations in Staphylococcus aureus isolates from meat products, including resistance to β-lactams, macrolides, aminoglycosides, tetracyclines, and others.
Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Healthy Turkeys and Broilers Using DNA Microarrays.
The study identified several AMR genes in MRSA isolates from healthy turkeys and broilers, including ermA, ermB, ermC, tetK, tetM, lnuA, mphC, vgaA, aadD, aphA3, blaZ, blaI, blaR, and mecA. These genes conferred resistance to various antibiotics such as erythromycin, clindamycin, tetracycline, lincomycin, macrolides, streptogramins, tobramycin, neomycin, kanamycin, and beta-lactam antibiotics.
Emergence of Nasal Carriage of ST80 and ST152 PVL+ Staphylococcus aureus Isolates from Livestock in Algeria.
The study identified the emergence of PVL+ Staphylococcus aureus isolates carrying resistance genes such as aphA3 and fosB in livestock in Algeria, highlighting the potential for cross-species transmission of these pathogens.
Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
The study identifies activating mutations in the quorum-sensing regulator Rgg2 of Streptococcus pyogenes, leading to constitutive activation of the quorum-sensing pathway. These mutations increase sensitivity to pheromones and alter inhibition by cyclosporine A.
Genomic and Epidemiological Evidence of a Dominant Panton-Valentine Leucocidin-Positive Methicillin Resistant Staphylococcus aureus Lineage in Sri Lanka and Presence Among Isolates From the United Kingdom and Australia.
The study identified a dominant PVL-positive ST5-MRSA-IVc clone in Sri Lanka, which was also found in the UK and Australia. The clone exhibited resistance to methicillin, erythromycin, tetracycline, gentamicin, and streptothricin.
MRSA Strains in Nepalese Rhesus Macaques (Macaca mulatta) and Their Environment.
The study identified several AMR genes in MRSA isolates from Rhesus macaques, environmental samples, and human patients in Nepal, including aacA-aadD, dfrA, erm(C), aacA-aphD, aphA3, sat, and blaZ.
Prevalence and characteristics of multidrug-resistant mcr-1-positive Escherichia coli isolates from broiler chickens in Tai'an, China.
The study identified mcr-1 as the primary cause of colistin resistance in E. coli isolates from broiler chickens in Tai'an, China, with high prevalence of multidrug resistance involving genes like bla TEM, bla CTX-M, aphA3, tetA, tetB, tetC, sul1, and sul2.
Characteristics of oral methicillin-resistant Staphylococcus epidermidis isolated from dental plaque.
The study identified multiple AMR genes in methicillin-resistant Staphylococcus epidermidis (MRSE) isolates from dental plaque, including mecA, dfrA, dfrG, aacA-aphD, aadD, aphA3, ermC, msrA, tetK, norA, qacA, and qacC. These genes confer resistance to various antibiotics such as oxacillin, penicillin G, trimethoprim, gentamicin, erythromycin, tetracycline, and quaternary ammonium compounds.
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study.
The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.
Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities.
The study identified various antimicrobial resistance genes in MRSA isolates from human, chicken, and environmental samples in Nigerian live bird markets, highlighting the presence of multidrug-resistant strains and the potential public health risks associated with their dissemination.
Early Inoculation of Microbial Suspension in Suckling Piglets Affects the Transmission of Maternal Microbiota and the Associated Antibiotic Resistance Genes.
The study shows that early inoculation of microbial suspensions affects the transmission of maternal microbiota and the associated antibiotic resistance genes (ARGs) in piglets. Specific ARGs such as aadE_2, aphA3, ermB, lnuB, vanTG, tetQ, tnpA, mpmB, lnuC, and tetW were found to be influenced by the inoculation of microbial suspensions S1 and S2.
Multidrug Resistance and Molecular Characterization of Streptococcus agalactiae Isolates From Dairy Cattle With Mastitis.
The study identified several AMR genes in S. agalactiae isolates from dairy cattle with mastitis, including tet(O), ermB, lnu(B), and aphA3, which confer resistance to tetracycline, erythromycin, clindamycin, pirlimycin, and kanamycin.
Molecular Characterization of Staphylococcus aureus Isolated from Human and Food Samples in Northern Algeria.
The study identified several antimicrobial resistance genes in Staphylococcus aureus isolates from human and food samples in northern Algeria, including blaZ, ermB, ermC, aphA3, sat, tetK, and tetM.
Antimicrobial and Biocide Resistance among Feline and Canine Staphylococcus aureus and Staphylococcus pseudintermedius Isolates from Diagnostic Submissions.
The study identified various antimicrobial resistance genes in feline and canine Staphylococcus aureus and Staphylococcus pseudintermedius isolates, including blaZ, mecA, mecC, tet(K), tet(M), erm(A), erm(B), erm(C), erm(T), msr(A), aadE, aacA-aphD, aphA3, aadD, dfrG, lnu(B), and lsa(E). These genes conferred resistance to multiple antibiotics such as penicillins, tetracyclines, macrolides, aminoglycosides, and others.
How Streptococcus suis escapes antibiotic treatments.
The study characterizes various AMR genes and mutations in Streptococcus suis, highlighting resistance to beta-lactams, macrolides, lincosamides, streptogramins, amphenicols, pleuromutilins, tetracyclines, sulfonamides, trimethoprim, and fluoroquinolones.
Antibiotic resistance genes and molecular typing of Streptococcus agalactiae isolated from pregnant women.
The study identified several antibiotic resistance genes in Streptococcus agalactiae isolates from pregnant women, including ermB, mefA/E, ermTR, tetM, tetO, and aphA3, which confer resistance to macrolides, tetracyclines, and aminoglycosides.
Molecular epidemiology, drug resistance, and virulence gene analysis of Streptococcus agalactiae isolates from dairy goats in backyard farms in China.
The study identified multiple AMR genes in S. agalactiae isolates from dairy goats in China, including pbp2b, tetL, tetM, tetK, tetO, ermA, ermB, mefA, aphA3, aad6, lnu(B), gryA, and parC, which confer resistance to various antibiotics such as penicillins, tetracyclines, macrolides, aminoglycosides, lincosamides, and quinolones.
An in-house 45-plex array for the detection of antimicrobial resistance genes in Gram-positive bacteria.
The study describes an in-house 45-plex array for detecting antimicrobial resistance genes in Gram-positive bacteria, identifying optrA, poxtA, and vanA as significant resistance markers in Enterococcus and Staphylococcus isolates.
Pathogenic Potential and Antibiotic Susceptibility: A Comprehensive Study of Enterococci from Different Ecological Settings.
The study identified several antibiotic resistance genes in Enterococcus isolates, including ermB (macrolide resistance), vanA (glycopeptide resistance), aphA3 (aminoglycoside resistance), aac6′-aph2″ (aminoglycoside resistance), and cat pIP501 (chloramphenicol resistance).
Emergence of novel methicillin resistant Staphylococcus pseudintermedius lineages revealed by whole genome sequencing of isolates from companion animals and humans in Scotland.
The study identified novel methicillin-resistant Staphylococcus pseudintermedius (MRSP) lineages, including ST726 and ST551, and characterized antimicrobial resistance genes such as mecA, blaZ, tetK, and mupA. It also noted a high prevalence of multidrug resistance (MDR) among MRSP isolates.
Molecular Epidemiology, Antimicrobial Resistance, and Virulence Profiles of Staphylococcus aureus from Fish, Aquatic Environments, and Fish Handlers in Southeast Nigeria.
The study identified 19 antimicrobial resistance genes in Staphylococcus aureus isolates from fish, aquatic environments, and fish handlers in Southeast Nigeria, highlighting the presence of multidrug-resistant strains with various resistance mechanisms.
Antibiotic resistance in mastitis-causing bacteria: Exploring antibiotic-resistance genes, underlying mechanisms, and their implications for dairy animal and public health.
The study identifies several AMR genes and mutations in Staphylococcus aureus and coagulase-negative staphylococci associated with mastitis, including blaZ, mecA, tetK, tetM, aphA3, aacA-aphD, aadD, ermA, msrA, mphC, lnuB, and vanA, which confer resistance to various antibiotics such as β-lactams, tetracyclines, aminoglycosides, macrolides, and glycopeptides.
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