Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
regulator of norA
Overview
DNA extraction of microbial DNA directly from infected tissue: an optimized protocol for use in nanopore sequencing.
The study presents an optimized DNA extraction protocol for improving the identification of Staphylococcus aureus and its antibiotic resistance genes from infected tissue using nanopore sequencing. The modified protocol significantly reduced human DNA content, enhancing the sensitivity of metagenomic sequencing. Several antibiotic resistance genes, including arlS, sav1866, norA, mepA, and tetC, were identified in S. aureus isolates from patients with orthopedic implant-related infections.
Characterization of methicillin-resistant Staphylococcus aureus through genomics approach.
The study characterized methicillin-resistant Staphylococcus aureus (MRSA) isolates, identifying genes such as mecA, blaZ, norA, gyrA, gyrB, tet-38, mepA, mepR, arlS, arlR, mgrA, clsA, dfrC, msbA, rpoB32, mprF, and mrpA, which confer resistance to various antibiotics.
Genomic analysis revealed a novel genotype of methicillin-susceptible Staphylococcus aureus isolated from a fatal sepsis case in dengue patient.
The study identified a novel genotype of methicillin-susceptible Staphylococcus aureus (HS-MSSA) that caused a fatal sepsis case. The strain carries a strain-specific blaZ-bearing plasmid, indicating resistance to penam antibiotics.
Prevalence and antimicrobial resistance profiling of Staphylococcus aureus isolated from traditional cheese in Yunnan, China.
The study identified 18 antimicrobial resistance genes in Staphylococcus aureus strain DC.RB_015, including mecA, blaZ, mepA, tet(K), tet(38), arlR, arlS, norA, mgrA, LmrS, APH(3′)-IIIa, aad(6), ErmB, SAT-4, mecR1, GlpT, murA, and bacA, which confer resistance to various antibiotics such as methicillin, beta-lactam, tetracycline, fluoroquinolone, macrolide, aminoglycoside, nucleoside, fosfomycin, and bacitracin.
Occurrence, Antibiotic Susceptibility, Biofilm Formation and Molecular Characterization of Staphylococcus aureus Isolated from Raw Shrimp in China.
The study identified multiple antibiotic resistance genes in Staphylococcus aureus isolates from raw shrimp in China, including mecA, mecR1, blaZ, aph(3')-IIIa, aad(6), ANT(4')-Ib, tet(K), mph(C), lnu(A), ermB, ermC, dfrC, dfrG, fosB, SAT-4, rpoB, msr(A), mepA, mepR, norA, mgrA, tet(38), sav1866, arlR, and arlS, which confer resistance to various antibiotics such as beta-lactams, aminoglycosides, tetracyclines, macrolides, lincosamides, streptogramins, trimethoprim, fosfomycin, and others.
Complete genome sequencing and comparative genomic analysis of three donkey Streptococcus equi subsp. equi isolates.
The study identified multiple antibiotic resistance genes in three donkey-derived Streptococcus equi subsp. equi isolates, including genes conferring resistance to beta-lactams, tetracyclines, macrolides, fluoroquinolones, and others. Notably, the HT1112 isolate showed resistance to six antimicrobials, while HTP133 and HTP232 showed resistance to fewer drugs. Additionally, the study highlighted the role of biofilm formation in antimicrobial resistance.
Hybrid Illumina-Nanopore assembly improves identification of multilocus sequence types and antimicrobial resistance genes of Staphylococcus aureus isolated from Vermont dairy farms: comparison to Illumina-only and R9.4.1 nanopore-only assemblies.
The study identified various antimicrobial resistance genes in Staphylococcus aureus isolates from Vermont dairy farms, including beta-lactam resistance genes (blaZ, blaI, blaR), tetracycline resistance genes (tet(K), tet(38)), erythromycin resistance genes (erm(T), erm(A)), lincomycin resistance gene (lnu(G)), aminoglycoside resistance genes (aaC3, ant(9)-la), multidrug resistance efflux pumps (lmrS, mepA, mepR, mepB, norA, norB, arlS, arlR, mgrA), and fosfomycin resistance gene (fosB).
Network analysis of antimicrobial resistance in Staphylococcus aureus: characterization of hub genes and their functional implications.
The study identifies hub genes involved in antimicrobial resistance in Staphylococcus aureus, including mecA, fosB, arlR, mepA, mgrA, arlS, and msrA2, which are associated with mechanisms such as efflux pump regulation, target protection, and target replacement.
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