Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
arsenate reductase
Overview
The chromosomal arsenic resistance genes of Thiobacillus ferrooxidans have an unusual arrangement and confer increased arsenic and antimony resistance to Escherichia coli.
The chromosomal arsenic resistance genes of Thiobacillus ferrooxidans, including arsB, arsC, and arsH, were cloned and shown to confer increased resistance to arsenic and antimony in Escherichia coli.
Novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti.
The study identifies a novel pathway for arsenic detoxification in Sinorhizobium meliloti involving the aquaglyceroporin AqpS and the arsenate reductase ArsC. AqpS facilitates the efflux of arsenite, while ArsC reduces arsenate to arsenite, providing resistance to arsenate.
Comparative Genomics and Phenotypic Investigations Into Antibiotic, Heavy Metal, and Disinfectant Susceptibilities of Salmonella enterica Strains Isolated in Australia.
The study identified several AMR genes and mutations in Salmonella enterica strains, including blaTEM-1, aph(3')-I, aph(6')-ld, dfrA5, tetA, and various arsenic resistance genes. A mutation in gyrA was also found to confer nalidixic acid resistance.
Characterization of an Environmental Multidrug-Resistant Acinetobacter seifertii and Comparative Genomic Analysis Reveals Co-occurrence of Antimicrobial Resistance and Metal Tolerance Determinants.
The study characterizes an environmental multidrug-resistant Acinetobacter seifertii isolate (SAb133) and identifies multiple antimicrobial resistance genes, metal tolerance genes, and virulence factors. Key findings include the presence of bla ADC–25, bla TEM, and various efflux pump genes, along with metal tolerance genes and virulence factors.
Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans.
The study identifies a cluster of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae sequence type 101 isolated from food and humans, highlighting the potential role of food as a source of multidrug-resistant bacteria transmission to humans.
Bacterial isolates harboring antibiotics and heavy-metal resistance genes co-existing with mobile genetic elements in natural aquatic water bodies.
The study identified blaTEM, AmpC, qnrS, merB, merP, merT, silE, silP, silS, arsC, IntI, SulI, ISecp1, TN3, and TN21 as significant AMR genes in bacterial isolates from Dal and Wular Lakes in Kashmir, India. These genes were found to confer resistance to various antibiotics and heavy metals, highlighting the co-existence of antibiotic and metal resistance determinants in aquatic environments.
Colonization of a hand washing sink in a veterinary hospital by an Enterobacter hormaechei strain carrying multiple resistances to high importance antimicrobials.
The study identified multiple antimicrobial resistance genes in an Enterobacter hormaechei strain isolated from a veterinary hospital sink, including blaSHV-12, qnrB2, and mcr-9.1, which confer resistance to cephalosporins, quinolones, and colistin, respectively.
Plasmid-Mediated Ampicillin, Quinolone, and Heavy Metal Co-Resistance among ESBL-Producing Isolates from the Yamuna River, New Delhi, India.
The study identified plasmid-mediated resistance genes bla CMY-2, bla CMY-42, qnrS, merB, merP, merT, and arsC in ESBL-producing isolates from the Yamuna River, indicating co-resistance to antibiotics and heavy metals.
A Novel Mobile Element ICERspD18B in Rheinheimera sp. D18 Contributes to Antibiotic and Arsenic Resistance.
The study characterizes the novel integrative and conjugative element ICE Rsp D18B in Rheinheimera sp. D18, which contains six antibiotic resistance genes (floR, sul2, strB, aph(3'')-Ib, and others) and an arsenic tolerance operon (arsRHCB), contributing to resistance against antibiotics and arsenic compounds.
Effects of in ovo probiotic administration on the incidence of avian pathogenic Escherichia coli in broilers and an evaluation on its virulence and antimicrobial resistance properties.
The study identified various antimicrobial resistance genes in APEC isolates, including blaTEM, aac(3)-VIa, aac(3)-VIb, aadA, tetA, tetB, dfr7, qacEΔ, qnr, sul1, intl1, arsC, and merA. These genes conferred resistance to multiple antibiotics such as beta-lactams, aminoglycosides, tetracyclines, quinolones, sulfonamides, and heavy metals.
Genomic Analysis of Staphylococcus aureus of the Lineage CC130, Including mecC-Carrying MRSA and MSSA Isolates Recovered of Animal, Human, and Environmental Origins.
The study identified several AMR genes in Staphylococcus aureus CC130 isolates, including mecC, blaZ, tet(K), arsB, and arsC. These genes conferred resistance to methicillin, penicillin, tetracycline, arsenite, and arsenate. The presence of the IEC system in some mecC-positive MRSA-CC130 strains suggests potential human adaptation.
Investigation of the Genes Involved in the Outbreaks of Escherichia coli and Salmonella spp. in the United States.
The study identified several antimicrobial resistance genes in E. coli and Salmonella spp., including aadA1, aph(3"-Ib, aph(6)-Id, blaTEM-1, sul2, tet(A), and tet(B) in E. coli, and arsA, arsB, arsC, iroB, and iroC in Salmonella spp. Additionally, virulence genes such as epeA, stxA2d, stxB2c, subA, and subB were found to be unique to outbreak E. coli.
A Novel Multidrug Resistant, Non-Tn4401 Genetic Element-Bearing, Strain of Klebsiella pneumoniae Isolated From an Urban Lake With Drinking and Recreational Water Reuse.
The study identifies a multidrug-resistant Klebsiella pneumoniae strain, ST5236, carrying the beta-lactamase gene blaCTX-M-15, the carbapenemase gene blaKPC-2, and the fosfomycin resistance gene fosA, along with efflux pumps oqxAB and acrAB, and heavy metal resistance genes fieF and arsC.
Mucilaginibacter sp. Strain Metal(loid) and Antibiotic Resistance Isolated from Estuarine Soil Contaminated Mine Tailing from the Fundão Dam.
The study identifies multiple AMR genes in Mucilaginibacter sp. 21p, including genes for resistance to quinolones, aminoglycosides, beta-lactamases, sulfonamides, tetracyclines, daptomycin, arsenic, zinc, manganese, cobalt, and cadmium. These genes are part of efflux pumps and other resistance mechanisms, indicating the strain's adaptability to metal(loid) and antibiotic stressors in contaminated environments.
Characterization of metal(loid)s and antibiotic resistance in bacteria of human gut microbiota from chronic kidney disease subjects.
The study identified several antibiotic and metal(loid) resistance genes in gut microbiota from chronic kidney disease (CKD) subjects, including genes encoding beta-lactamases, quinolone resistance proteins, macrolide phosphotransferases, and efflux pumps. Additionally, genes conferring resistance to arsenicals and heavy metals were detected.
Farming Practice Influences Antimicrobial Resistance Burden of Non-Aureus Staphylococci in Pig Husbandries.
The study found that organic and alternative pig farming practices are associated with reduced antimicrobial resistance (AMR) in non-aureus staphylococci (NAS) compared to conventional farming. Specific AMR genes such as mecA, blaZ, blaPC1, and others were more prevalent in conventional farms, while organic farms showed lower levels of AMR genes for aminoglycosides, phenicols, and tetracyclines.
The Plasmidomic Landscape of Clinical Methicillin-Resistant Staphylococcus aureus Isolates from Malaysia.
The study identified various plasmid-borne antimicrobial resistance genes in Malaysian MRSA isolates, including ermC, cat, tetK, tetL, aadD, aac(6')-Ie-aph(2")-Ia, lnuA, cadAC, cadDX, copB, mco, arsB, arsC, and qacA, contributing to multidrug resistance.
Study of heavy metal resistance genes in Escherichia coli isolates from a marine ecosystem with a history of environmental pollution (arsenic, cadmium, copper, and mercury).
The study identified several heavy metal resistance genes (HMRGs) in Escherichia coli isolates from a marine ecosystem with a history of environmental pollution, highlighting the prevalence of these genes and their potential interactions with antibiotic resistance genes.
Metalloproteomics Reveals Multi-Level Stress Response in Escherichia coli When Exposed to Arsenite.
The study identifies the arsRBC operon as crucial for arsenic resistance in E. coli, demonstrating that ArsR, ArsB, and ArsC contribute to resistance against arsenite through distinct mechanisms.
Zoonotic transmission of asymptomatic carriage Staphylococcus aureus on dairy farms in Canterbury, New Zealand.
The study identified a bovine isolate carrying the extended-spectrum beta-lactamase gene blaTEM-116, highlighting concerns about antimicrobial resistance in dairy farm environments. Multiple antimicrobial resistance genes were detected in both bovine and human isolates, including genes conferring resistance to tetracyclines, penicillins, fosfomycin, and aminoglycosides.
Wastewater based genomic surveillance key to population level monitoring of AmpC/ESBL producing Escherichia coli.
The study identified various AMR genes and mutations in AmpC/ESBL-producing E. coli from wastewater samples in Finland, highlighting the prevalence of blaCTX-M-15, blaCTX-M-27, and other resistance determinants.
Genomic characterisation of nasal isolates of coagulase-negative Staphylococci from healthy medical students reveals novel Staphylococcal cassette chromosome mec elements.
The study identified novel Staphylococcal cassette chromosome mec (SCC mec ) elements in four methicillin-resistant coagulase-negative Staphylococci (CoNS) isolates from healthy medical students. The isolates harbored various antimicrobial resistance genes, including mecA, blaZ, mphC, msrA, tetK, fusC, fusF, qacA, qacB, qacC, norA, copB, arsC, cadC, cadD, copZ, copA, copR, and czcD, which conferred resistance to beta-lactams, macrolides, tetracyclines, fusidic acid, quaternary ammonium compounds, fluoroquinolones, and heavy metals.
Cefiderocol-resistant pathogens in German hospital wastewater: a reservoir for multidrug resistance.
The study identifies multiple AMR genes, including bla NDM−1, bla VIM−1, bla OXA−48, and bla KPC−2, in cefiderocol-resistant isolates from German hospital wastewater, highlighting the presence of multidrug-resistant pathogens with diverse resistance mechanisms.
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