bc2h

zinc metallo-beta-lactamase

Validation StatusCandidate

Overview

Mechanism: confers resistance to penicillins, carbapenems, and cephalosporins
Validation Method: detected via ABRIcate and MEGARes 2.0 database
Drug Classes: Penicillin, Carbapenem, Cephalosporin
Organisms: Bacillus cereus group
Geographic Location: Europe
Papers: 1
Databases: Reslit

Papers1

Comparative Analysis of Bacillus cereus Group Isolates' Resistance Using Disk Diffusion and Broth Microdilution and the Correlation between Antimicrobial Resistance Phenotypes and Genotypes.

PMID 35225691 · 2022

The study identified several antimicrobial resistance genes in Bacillus cereus group isolates, including beta-lactamase-encoding genes (bla1, blaZ, blaTEM), mph for erythromycin resistance, rph for rifampicin resistance, and fosB for fosfomycin resistance. These genes were detected using ABRIcate and MEGARes 2.0 database, and their association with resistance phenotypes was analyzed.

Gene Information

Gene Name: bc2h
Allele: Bc
Encodes: zinc metallo-beta-lactamase
Source Database: Reslit
Mechanism: confers resistance to penicillins, carbapenems, and cephalosporins
Confers Resistance To: PenicillinCarbapenemCephalosporin
Organisms Tested In: • Bacillus cereus group
Geographic Location: Europe
Validation Method: detected via ABRIcate and MEGARes 2.0 database

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bc2h

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