blaACT

beta-lactamase

Validation StatusCandidate

Overview

Mechanism: hydrolysis of beta-lactam antibiotics
Validation Method: PCR and sequencing
Drug Classes: cefoxitin
Organisms: Klebsiella pneumoniae
Geographic Location: United States
Papers: 1
Databases: Reslit

Papers1

Occurrence of newer beta-lactamases in Klebsiella pneumoniae isolates from 24 U.S. hospitals.

PMID 12435685 · 2002

The study identified several beta-lactamases, including bla DHA-1, bla ACT-1, bla FOX-5, bla CMY-2, and bla KPC-2, in Klebsiella pneumoniae isolates from 24 U.S. hospitals. These enzymes confer resistance to various beta-lactam antibiotics.

Gene Information

Gene Name: blaACT
Allele: blaACT-1
Encodes: beta-lactamase
Source Database: Reslit
Mechanism: hydrolysis of beta-lactam antibiotics
Confers Resistance To: cefoxitin
Organisms Tested In: • Klebsiella pneumoniae
Geographic Location: United States
Validation Method: PCR and sequencing
Sequence Accession: AF055067|X77455|X91840|U58495|X04730

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blaACT

Gene Information