blaADC

beta-lactamase

Validation StatusCandidate

Overview

Validation Method: expression in E. coli DH10B and MIC testing
Drug Classes: cefepime, ceftazidime, cefotaxime
Organisms: Acinetobacter baumannii, Escherichia coli DH10B
Papers: 1
Databases: Reslit

Papers1

Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes.

PMID 15980372 · 2005

The study identifies a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase, which confers resistance to several cephalosporins including cefepime, ceftazidime, and cefotaxime.

Gene Information

Gene Name: blaADC
Allele: blaADC-7
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: cefepimeceftazidimecefotaxime
Organisms Tested In: • Acinetobacter baumannii
• Escherichia coli DH10B
Validation Method: expression in E. coli DH10B and MIC testing
Sequence Accession: AY648950

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blaADC

Gene Information