Browse AMR Genes

Explore antimicrobial resistance genes from the literature

blaARL

beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to blaARL

Browse AMR rules for blaARL

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic inactivation
Validation Method: expression in S. aureus and nitrocefin test
Drug Classes: Penicillin, BETA-LACTAM
Organisms: Staphylococcus aureus, Staphylococcus arlettae
Geographic Location: Somalia|Kenya|East Africa, Switzerland|Sweden|Belgium|Kenya
Alleles: 7
Papers: 2
Databases: Card DatabaseReference Gene CatalogReslit

Allele Variants7

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
blaARL	Reslit	2	Penicillin	Staphylococcus aureus +1	Switzerland\|Sweden\|Belgium\|Kenya, Somalia\|Kenya\|East Africa	2017, 2022	KY363215\|KY464892\|KY363206\|KY363207\|KY363208\|KY363209\|KY363210\|KY363211\|KY363212\|KY363213\|KY363214	-
blaARL-5

Papers2

1

Novel beta-lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

The study identifies a novel beta-lactamase gene, blaARL, in Staphylococcus arlettae, which confers intrinsic penicillin resistance. The gene was functionally validated through expression in S. aureus and demonstrated resistance to penicillin.

Gene Information

Gene Name: blaARL
Allele: blaARL
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: Penicillin
Organisms Tested In: • Staphylococcus aureus
• Staphylococcus arlettae
Geographic Location: Switzerland|Sweden|Belgium|Kenya
Validation Method: expression in S. aureus and nitrocefin test
Sequence Accession: KY363215|KY464892|KY363206|KY363207|KY363208|KY363209|KY363210|KY363211|KY363212|KY363213|KY363214

2

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-5
Encodes: class A beta-lactamase ARL-5, ARL Beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363214.1
Protein Accession: APY23862.1
Notes: ARO:3004738

3

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-6
Encodes: class A beta-lactamase ARL-6
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY464892.1
Protein Accession: APY23865.1
Notes: ARO:3004739

4

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-6
Encodes: class A beta-lactamase ARL-6, ARL Beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY464892.1
Protein Accession: APY23865.1
Notes: ARO:3004739

5

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-1
Encodes: class A beta-lactamase ARL-1
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363213.1
Protein Accession: APY23859.1
Notes: ARO:3004734

6

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-1
Encodes: class A beta-lactamase ARL-1
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363213.1
Protein Accession: APY23859.1
Notes: ARO:3004734

7

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-2
Encodes: class A beta-lactamase ARL-2
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363207.1
Protein Accession: APY23841.1
Notes: ARO:3004735

8

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-2
Encodes: class A beta-lactamase ARL-2, ARL Beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363207.1
Protein Accession: APY23841.1
Notes: ARO:3004735

9

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-3
Encodes: class A beta-lactamase ARL-3
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363208.1
Protein Accession: APY23844.1
Notes: ARO:3004736

10

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-3
Encodes: class A beta-lactamase ARL-3, ARL Beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363208.1
Protein Accession: APY23844.1
Notes: ARO:3004736

11

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-4
Encodes: class A beta-lactamase ARL-4
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363206.1
Protein Accession: APY23838.1
Notes: ARO:3004737

12

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-4
Encodes: class A beta-lactamase ARL-4, ARL Beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363206.1
Protein Accession: APY23838.1
Notes: ARO:3004737

13

Novel β-Lactamase bla(ARL) in Staphylococcus arlettae.

PMID 28497118 · 2017

Gene Information

Gene Name: blaARL
Allele: blaARL-5
Encodes: class A beta-lactamase ARL-5
Source Database: Reference Gene Catalog
Mechanism: antibiotic inactivation
Confers Resistance To: BETA-LACTAM
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363214.1
Protein Accession: APY23862.1
Notes: ARO:3004738

14

Genomic Characterization and Antimicrobial Susceptibility of Dromedary-Associated Staphylococcaceae from the Horn of Africa.

PMID 36226992 · 2022

The study identified several antimicrobial resistance genes in Staphylococcaceae isolates from camels and cattle in East Africa, including tet(K), blaZ, blaARL, mecA, mecA1, msrA, mphC, salA, dfrG, aacA-aphD, and str. These genes were associated with resistance to tetracycline, benzylpenicillin, oxacillin, erythromycin, clindamycin, trimethoprim, gentamicin, and streptomycin.

Gene Information

Gene Name: blaARL
Allele: blaARL
Encodes: group II beta-lactamase
Source Database: Reslit
Confers Resistance To: Penicillin
Organisms Tested In: • Staphylococcus arlettae
Geographic Location: Somalia|Kenya|East Africa
Validation Method: phenotypic and genotypic data matching
Sequence Accession: PRJNA819273

15

Gene Information

Gene Name: blaARL
Allele: blaARL-1
Encodes: ARL Beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • Staphylococcus arlettae
Sequence Accession: KY363215.1
Protein Accession: APY23733.1
Notes: ARO:3004734