Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaBRO-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 7 | Ampicillin, Penicillin +10 | Moraxella porci +1 |
| Great Britain, Europe |
| 1996, 2017, 2022, 2023, 2024 |
| MF176238|MF176239|MF176240 |
| AAA92126.1 |
| blaBRO-type | Reslit | 1 | Ampicillin, Ceftazidime | Haemophilus influenzae +1 | Switzerland | 2019 | PRJEB24475 | - |
| blaBRO-2 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | Ampicillin, Penicillin +9 | Moraxella catarrhalis +2 | Europe | 1996, 2022, 2024 | SAMEA7160394|SAMEA7160393|SAMEA7160392|SAMEA7160391|SAMEA7160390|SAMEA7160389|SAMEA7160388|SAMEA7160387|SAMEA7160386|SAMEA7160385|SAMEA7160384|SAMEA7160383|SAMEA7160382|SAMEA7160381|SAMEA7160380|SAMEA7160379|SAMEA7160378|SAMEA7160377 | CAA90891.1 |
mcr-1 and mcr-2 variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015.
The study identifies mcr-1.10 and mcr-2.2 variant genes in Moraxella species isolated from pigs in Great Britain, along with eptA, which confer resistance to colistin. Additionally, bla BRO-1 and tetL genes were found to confer resistance to ampicillin and tetracycline respectively.
Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life.
The study identified various antimicrobial resistance genes in the nasal microbiome of infants with cystic fibrosis, including beta-lactamases, chloramphenicol efflux pumps, tetracycline resistance proteins, and enzymes involved in folic acid synthesis inhibition.
The characterization of Moraxella catarrhalis carried in the general population.
The study characterized the diversity of Moraxella catarrhalis isolates from the upper respiratory tract of healthy individuals, identifying a low prevalence of antimicrobial resistance and high prevalence of various virulence factor genes. It found that beta-lactamase genes bla BRO-1 and bla BRO-2 were present in all isolates, contributing to resistance against beta-lactam antibiotics.
The characterization of Moraxella catarrhalis carried in the general population.
The study characterized the diversity of Moraxella catarrhalis isolates from the upper respiratory tract of healthy individuals, identifying a low prevalence of antimicrobial resistance and high prevalence of various virulence factor genes. It found that beta-lactamase genes bla BRO-1 and bla BRO-2 were present in all isolates, contributing to resistance against beta-lactam antibiotics.
Genomic classification and antimicrobial resistance profiling of Streptococcus pneumoniae and Haemophilus influenza isolates associated with paediatric otitis media and upper respiratory infection.
The study identified beta-lactamase genes blaTEM-1 and blaROB-1 in Haemophilus influenzae isolates, which were validated through WGS-based prediction and clinical testing.
Phylogenetic Lineages and Diseases Associated with Moraxella catarrhalis Isolates Recovered from Bulgarian Patients.
The study identified that all M. catarrhalis strains were resistant to penicillin, aminopenicillins, and first-generation cephalosporins due to the presence of BRO-1 and BRO-2 beta-lactamases. The strains exhibited high susceptibility to other antibiotics, with only a small percentage showing resistance to trimethoprim-sulfamethoxazole.
Phylogenetic Lineages and Diseases Associated with Moraxella catarrhalis Isolates Recovered from Bulgarian Patients.
The study identified that all M. catarrhalis strains were resistant to penicillin, aminopenicillins, and first-generation cephalosporins due to the presence of BRO-1 and BRO-2 beta-lactamases. The strains exhibited high susceptibility to other antibiotics, with only a small percentage showing resistance to trimethoprim-sulfamethoxazole.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
Molecular characterization of the BRO beta-lactamase of Moraxella (Branhamella) catarrhalis.
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