blaCAU

metallo-beta-lactamase

Validation StatusCandidate

Overview

Validation Method: expression in E. coli and enzymatic activity assay
Drug Classes: carbapenems, penicillins, cephalosporins
Organisms: Escherichia coli, Caulobacter crescentus
Papers: 1
Databases: Reslit

Papers1

CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome.

PMID 12019096 · 2002

The study identifies CAU-1, a novel subclass B3 metallo-beta-lactamase from Caulobacter crescentus, which exhibits activity against carbapenems, penicillins, and certain cephalosporins.

Gene Information

Gene Name: blaCAU
Allele: blaCAU-1
Encodes: metallo-beta-lactamase
Source Database: Reslit
Confers Resistance To: carbapenemspenicillinscephalosporins
Organisms Tested In: • Escherichia coli
• Caulobacter crescentus
Validation Method: expression in E. coli and enzymatic activity assay
Sequence Accession: AJ308331

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blaCAU

Gene Information