Mutations

Protein ChangeNucleotide ChangeMechanismOrganismResistance ToDatabaseValidation Status
G214E--E. coli
cefotaxime|aztreonam
Reslit
Candidate
Papers1
1

Enhancing resistance to cephalosporins in class C beta-lactamases: impact of Gly214Glu in CMY-2.

PMID 19938877 · 2010

The Gly214Glu substitution in CMY-32 enhances resistance to cefotaxime and aztreonam compared to CMY-2.

Mutation Information

Protein Change
G214E
Organisms
E. coli
Confers Resistance To
cefotaxime|aztreonam
Source Database
Reslit