blaERP

class A beta-lactamase

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Enzymatic inactivation
Validation Method: cloning in E. coli + MIC testing
Drug Classes: Ampicillin, Amoxicillin, Ticarcillin, Piperacillin, Cephalothin, Ceftriaxone, Ceftazidime, Cefepime, Aztreonam, TICARCILLIN, CEPHALOSPORIN, AMOXICILLIN, AMPICILLIN, PIPERACILLIN, Cephalosporin, Penicillin
Organisms: Erwinia persicina, Escherichia coli, Erwinia persicin
Geographic Location: Berkeley, California
Papers: 2
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers2

Identification of a Chromosome-Borne Expanded-Spectrum Class A beta-lactamase from Erwinia persicina.

PMID 12384342 · 2002

The study identifies a novel chromosome-borne extended-spectrum class A beta-lactamase, blaERP-1, from Erwinia persicina, which confers resistance to various β-lactam antibiotics.

Gene Information

Gene Name: blaERP
Allele: blaERP-1
Encodes: class A beta-lactamase
Source Database: Reslit
Confers Resistance To: AmpicillinAmoxicillinTicarcillinPiperacillinCephalothinCeftriaxoneCeftazidimeCefepimeAztreonam
Organisms Tested In: • Erwinia persicina
• Escherichia coli
Validation Method: cloning in E. coli + MIC testing
Sequence Accession: AY077733

Identification of a chromosome-borne expanded-spectrum class a beta-lactamase from Erwinia persicina.

PMID 12384342 · 2002

Gene Information

Gene Name: blaERP
Allele: blaERP-1
Encodes: extended-spectrum class A beta-lactamase ERP-1
Source Database: Reference Gene Catalog
Mechanism: Enzymatic inactivation
Confers Resistance To: TICARCILLINCEPHALOSPORINAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Erwinia persicina
Sequence Accession: AY077733.1
Protein Accession: AAL86999.1
Notes: Chromosomal class A beta-lactamase

Identification of a chromosome-borne expanded-spectrum class a beta-lactamase from Erwinia persicina.

PMID 12384342 · 2002

Gene Information

Gene Name: blaERP
Allele: blaERP-1
Encodes: extended-spectrum class A beta-lactamase ERP-1
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: TICARCILLINCEPHALOSPORINAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Erwinia persicina
Sequence Accession: AY077733.1
Protein Accession: AAL86999.1
Notes: Chromosomal class A beta-lactamase

Identification of a chromosome-borne expanded-spectrum class a beta-lactamase from Erwinia persicina.

PMID 12384342 · 2002

Gene Information

Gene Name: blaERP
Allele: blaERP-1
Encodes: extended-spectrum class A beta-lactamase ERP-1, ERP beta-lactamase
Source Database: Card Database
Mechanism: Enzymatic inactivation, antibiotic inactivation
Confers Resistance To: TICARCILLINCEPHALOSPORINAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Erwinia persicina
Sequence Accession: AY077733.1
Protein Accession: AAL86999.1
Notes: Chromosomal class A beta-lactamase, ARO:3004782

Identification of a chromosome-borne expanded-spectrum class a beta-lactamase from Erwinia persicina.

PMID 12384342 · 2002

Gene Information

Gene Name: blaERP
Allele: blaERP-1
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: AMOXICILLINPIPERACILLINAMPICILLINTICARCILLIN
Organisms Tested In: • Erwinia persicina
Sequence Accession: AY077733
Notes: Chromosomal class A beta-lactamase

Identification of novel antimicrobial resistance genes from microbiota on retail spinach.

PMID 24289541 · 2013

The study identified novel antimicrobial resistance genes from microbiota on retail spinach, including beta-lactamases, a pentapeptide repeat protein, a penicillin binding protein, and putative dihydrofolate reductase genes, which confer resistance to various antibiotics such as cephalosporins, fluoroquinolones, and trimethoprim.

Gene Information

Gene Name: blaERP
Allele: blaERP-1
Encodes: Extended Spectrum Beta-lactamase
Source Database: Reslit
Confers Resistance To: CephalosporinPenicillin
Organisms Tested In: • Erwinia persicin
• Escherichia coli
Geographic Location: Berkeley, California
Validation Method: Transformation into E. coli host and measurement of MIC
Sequence Accession: KF791056|KF791057|KF791058|KF791059|KF791060

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blaERP

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