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Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
carbapenem-hydrolyzing metallo-beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| bla_ESP-1 | Reslit | 1 | Meropenem | Epilithonimonas tenax +1 | Denmark|United Kingdom|Germany|Spain|Norway|Algeria | 2016 | KP109675|KP109676|KP109677|KP109678|KP109679|KP109680|KP109681 | - |
| blaESP-1 |
| 3 |
| CARBAPENEM, Carbapenem |
| Chryseobacterium sp. Stok-2 |
| Stellenbosch, South Africa |
| 2016, 2022 |
| KP109681.1 |
| AJP77085.1 |
| blaESP-2 | Reslit | 1 | Imipenem, Ampicillin +5 | Escherichia coli | Denmark|Germany|Algeria|Spain|Norway | 2016 | KU167035|KU167036|KU167037|KU167038|KU167039|KU167040|KU167041|KU167042|KU167043 | - |
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing beta-lactamases of Potential Clinical Relevance.
The study identifies seven new carbapenem-hydrolyzing metallo-beta-lactamases (MBLs) from soil bacteria, including bla_CPS-1, bla_ESP-1, bla_PEDO-1, bla_SPG-1, and bla_MSI-1, which confer resistance to various β-lactam antibiotics when expressed in E. coli.
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing β-Lactamases of Potential Clinical Relevance.
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing β-Lactamases of Potential Clinical Relevance.
Expanding the Repertoire of Carbapenem-Hydrolyzing Metallo-ß-Lactamases by Functional Metagenomic Analysis of Soil Microbiota.
Nine carbapenem-hydrolyzing metallo-beta-lactamases (MBLs) were identified in soil microbiota using functional metagenomics. These MBLs included two subclass B1 (GRD23-1 and SPN79-1) and seven subclass B3 (CRD3-1, PEDO-1, GRD33-1, ESP-2, ALG6-1, ALG11-1, and DHT2-1). All MBLs conferred resistance to various β-lactam antibiotics in E. coli.
Spatiotemporal Investigation of Antibiotic Resistance in the Urban Water Cycle Influenced by Environmental and Anthropogenic Activity.
The study identified several AMR genes, including carbapenemases (cphA5, cphA7, imiH, ESP-1), colistin resistance gene mcr-7.1, aminoglycoside resistance genes (aadA, aph(6)-Id, aph(3')-Ib), sulfonamide/trimethoprim resistance genes (sul1, dfrA15, dfrA14), and multidrug efflux pumps (MexB, OpmH, MexK) in various bacterial isolates from urban water samples.
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