Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaSFO-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 12 | Cefoxitin, Cefotaxime +20 |
| Spain, China, Bulgaria|Europe, Spain|China|Taiwan |
| 1999, 2011, 2017, 2022, 2024, 2025 |
| FJ848785 |
| BAA76882.1 |
| blaFONA-1 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, UNKNOWN BETA-LACTAM | Serratia fonticola | - | 2014 | AJ251239.1 | CAB61635.1 |
| blaFONA-5 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | BETA-LACTAM, UNKNOWN BETA-LACTAM +3 | Serratia fonticola | United States | 2014, 2022 | AJ251243.1 | CAB61643.1 |
| blaFONA-2 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, UNKNOWN BETA-LACTAM | Serratia fonticola | - | 2014 | AJ251240.1 | CAB61637.1 |
| blaFONA-3 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, UNKNOWN BETA-LACTAM | Serratia fonticola | - | 2014 | AJ251241.1 | CAB61639.1 |
| blaFONA-4 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, UNKNOWN BETA-LACTAM | Serratia fonticola | - | 2014 | AJ251242.1 | CAB61641.1 |
| blaFONA-6 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, UNKNOWN BETA-LACTAM | Serratia fonticola | - | 2014 | AJ251244.1 | CAB61645.1 |
| blaFONA-13 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | 2023 | ON713465.1 | USH09262.1 |
| blaFONA-11 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | 2023 | ON713463.1 | USH09260.1 |
| blaFONA-12 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | 2023 | ON713464.1 | USH09261.1 |
| blaFONA-8 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | 2023 | ON713460.1 | USH09257.1 |
| blaFONA-9 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | 2023 | ON713461.1 | USH09258.1 |
| blaFONA-10 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | 2023 | ON713462.1 | USH09259.1 |
| blaFONA-7 | Card DatabaseReference Gene Catalog | 2 | BETA-LACTAM | Serratia fonticola | - | - | MN634199.1 | QGF22214.1 |
Emergence in Spain of a multidrug-resistant Enterobacter cloacae clinical isolate producing SFO-1 extended-spectrum beta-lactamase.
The study describes the first outbreak in Spain involving an SFO-1-producing Enterobacter cloacae strain, which exhibits multidrug resistance primarily due to the SFO-1 extended-spectrum beta-lactamase.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Extended spectrum ß-lactamase- and constitutively AmpC-producing Enterobacteriaceae on fresh produce and in the agricultural environment.
Molecular Characteristics of Class A beta-lactamases
The paper characterizes various class A beta-lactamases, including TEM-1, GIL-1, OXY, CTX-M, SFO-1, CARBA, GES, PER-1, and VEB-1, highlighting their roles in conferring resistance to β-lactam antibiotics such as penicillins, cephalosporins, and carbapenems.
A novel Tn1696-like composite transposon (Tn6404) harboring bla (IMP-4) in a Klebsiella pneumoniae isolate carrying a rare ESBL gene bla (SFO-1).
The study identifies a novel Tn1696-like transposon (Tn6404) harboring the carbapenemase gene blaIMP-4 and the rare ESBL gene blaSFO-1 in a multidrug-resistant Klebsiella pneumoniae isolate. Both genes were experimentally validated for their resistance mechanisms.
Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States.
The study identified AmpC- and ESBL-producing Enterobacterales in fresh vegetables in the United States, including the first isolation of multidrug-resistant ESBL-producing E. hormaechei carrying the mcr-9 resistance gene.
Epidemiology of Klebsiella michiganensis Carrying Multidrug-Resistant IncHI5 Plasmids in the Southeast Coastal Area of China.
The study identified multiple AMR genes on IncHI5 plasmids in Klebsiella michiganensis, including beta-lactamases (blaCTX-M-3, blaTEM-1, blaSHV-12, blaIMP-4, blaNDM-1, blaOXA-1, blaOXA-16, blaSFO-1, blaSIM-1), aminoglycoside modifying enzymes (aacA4, arr3, aadA5, gcu37, dfrA1), chloramphenicol acetyltransferase (catA2), streptomycin resistance genes (strA, strB), macrolide resistance genes (msrAB, mph(A)), and quaternary ammonium compound resistance gene (qacG2).
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Evaluation of a Lateral Flow Immunoassay for Rapid Detection of CTX-M Producers from Blood Cultures.
Genomic Characterization of 16S rRNA Methyltransferase-Producing Enterobacterales Reveals the Emergence of Klebsiella pneumoniae ST6260 Harboring rmtF, rmtB, bla(NDM-5), bla(OXA-232) and bla(SFO-1) Genes in a Cancer Hospital in Bulgaria.
The study identifies the emergence of Klebsiella pneumoniae ST6260 harboring multiple AMR genes, including rmtF, rmtB, bla(NDM-5), bla(OXA-232), and bla(SFO-1), highlighting the complexity of resistance mechanisms in Enterobacterales.
Broad spectrum of β-lactamase coverage and potent antimicrobial activity of xeruborbactam in combination with meropenem against carbapenemase-producing Enterobacterales, including strains resistant to new β-lactam/β-lactamase inhibitor combinations.
Xeruborbactam in combination with meropenem shows potent activity against carbapenemase-producing Enterobacterales, including strains resistant to other β-lactam/β-lactamase inhibitor combinations. Specific β-lactamases like blaIMP-23 and blaSPM-1 were identified as resistant to xeruborbactam.
Clonal dissemination of carbapenem-resistant ST477 Klebsiella michiganensis co-producing NDM-1, SFO-1, and VEB-3 in a Chinese hospital.
The study identifies the clonal dissemination of carbapenem-resistant ST477 Klebsiella michiganensis co-producing NDM-1, SFO-1, and VEB-3 in a Chinese hospital, highlighting the role of a self-transmissible plasmid in the spread of these resistance genes.
Characterization of SFO-1, a plasmid-mediated inducible class A beta-lactamase from Enterobacter cloacae.
Characterization of SFO-1, a plasmid-mediated inducible class A beta-lactamase from Enterobacter cloacae.
Characterization of SFO-1, a plasmid-mediated inducible class A beta-lactamase from Enterobacter cloacae.
Characterization of SFO-1, a plasmid-mediated inducible class A beta-lactamase from Enterobacter cloacae.
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