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Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaGES-1 | Reslit | 2 | ceftazidime, cephalosporins | Klebsiella pneumoniae +1 | France|French Guiana, Portugal | 2000, 2003 | AF156486 | - |
| blaGES-2 | Reslit |
| 1 |
| imipenem |
| Pseudomonas aeruginosa +1 |
| South Africa |
| 2001 |
| AF326355 |
| - |
| blaGES-3 | Reslit | 1 | ceftazidime | Klebsiella pneumoniae +1 | Japan | 2004 | AB113580 | - |
| blaGES-4 | Reslit | 1 | cefoxitin, imipenem +1 | Klebsiella pneumoniae +1 | Japan | 2004 | AB116260|AB116723 | - |
| blaGES-9 | Reslit | 1 | aztreonam | Pseudomonas aeruginosa +1 | France | 2005 | AY920928 | - |
Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae.
The study identified GES-1, a novel class A extended-spectrum beta-lactamase, which confers resistance to ceftazidime. It was cloned and expressed in E. coli, demonstrating its role in beta-lactam resistance.
GES-2, a class A beta-lactamase from Pseudomonas aeruginosa with increased hydrolysis of imipenem.
The study identifies GES-2, a class A beta-lactamase from Pseudomonas aeruginosa, which exhibits increased hydrolysis of imipenem compared to GES-1.
Molecular characterization of a new class 3 integron in Klebsiella pneumoniae.
The study identifies a new class 3 integron in Klebsiella pneumoniae FFUL 22K carrying the blaGES-1 gene cassette, which confers resistance to extended-spectrum cephalosporins.
Nosocomial spread of ceftazidime-resistant Klebsiella pneumoniae strains producing a novel class a beta-lactamase, GES-3, in a neonatal intensive care unit in Japan.
The study identifies a novel class A beta-lactamase, GES-3, which confers resistance to ceftazidime in ceftazidime-resistant Klebsiella pneumoniae strains isolated from a neonatal intensive care unit in Japan.
Molecular characterization of a cephamycin-hydrolyzing and inhibitor-resistant class A beta-lactamase, GES-4, possessing a single G170S substitution in the omega-loop.
The study identifies GES-4, a class A beta-lactamase with a G170S substitution in the omega-loop, which confers resistance to cephamycins and carbapenems and exhibits inhibitor resistance.
Integron-encoded GES-type extended-spectrum beta-lactamase with increased activity toward aztreonam in Pseudomonas aeruginosa.
The study identifies a novel GES-type extended-spectrum beta-lactamase, GES-9, which exhibits increased activity towards aztreonam in Pseudomonas aeruginosa. The gene is located in a class 1 integron and shows resistance to several beta-lactam antibiotics.
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