Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Overview
Reslit |
| Candidate |
| D179Q | - | - | Escherichia coli | Ceftazidime/avibactam | Reslit | Candidate |
| R164A | - | - | Escherichia coli | Ceftazidime/avibactam | Reslit | Candidate |
| H121R | - | - | E. coli | Carbapenem | Reslit | Candidate |
| R164S | - | - | Klebsiella pneumoniae | Carbapenem | Reslit | Candidate |
Activity of ceftazidime/avibactam against isogenic strains of Escherichia coli containing KPC and SHV β-lactamases with single amino acid substitutions in the Ω-loop.
Antibiotic resistance in Pakistan: a systematic review of past decade.
Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.
the Asp179Asn substitution leads to resistance mechanisms involving structural changes in the active site
Class A Carbapenemases: Mechanisms of Action and Resistance
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