blaNDM-5

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
P59A	-	-	E. coli	Carbapenem	Reslit	Candidate
-	G5561A	reduces blaNDM-5 expression, leading to decreased carbapenem resistance	Escherichia coli	Carbapenem	Reslit	Candidate

Papers2

Phylogenetic diversity and mutational analysis of New Delhi Metallo-β-lactamase (NDM) producing E. coli strains from pediatric patients in Pakistan.

A Natural Novel Mutation in the bla(NDM-5) Promoter Reducing Carbapenems Resistance in a Clinical Escherichia coli Strain.

The mutation reduces blaNDM-5 expression, leading to decreased carbapenem resistance.

Nucleotide Change: G5561A
Organisms: Escherichia coli
Confers Resistance To: Carbapenem
Effect on Function: reduces blaNDM-5 expression, leading to decreased carbapenem resistance
Source Database: Reslit