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blaOXA-423

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to blaOXA-423

Browse AMR rules for blaOXA-423

Overview

Drug Classes: Penicillin|Carbapenem
Organisms: Acinetobacter baumannii, E. coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
V128A	-	weaker hydrolytic capacity	Acinetobacter baumannii, E. coli	Penicillin\|Carbapenem	Reslit	Candidate

Papers1

1

Carbapenemase OXA-423: A Novel OXA-23 Variant in Acinetobacter baumannii.

PMID 33204124 · 2020

The Val128Ala substitution is located at the conserved active-site motif SAV of OXA-23.

Mutation Information

blaOXA-423: p.V128A

Protein Change: V128A
Organisms: Acinetobacter baumannii, E. coli
Confers Resistance To: Penicillin|Carbapenem
Effect on Function: weaker hydrolytic capacity
Source Database: Reslit