Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
inhibitor-resistant extended spectrum class C beta-lactamase PAC-2
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaPAC-2 | Reference Gene CatalogReslit | 2 | CEPHALOSPORIN, ceftazidime avibactam | Klebsiella quasipneumoniae subsp. quasipneumoniae +5 | Colombia | 2025 | PQ567105.1 | XKB79099.1 |
| blaPAC-1 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, carbapenems +4 | Pseudomonas aeruginosa +1 | Pakistan, Singapore|Afghanistan|France|Nepal, Egypt | 2015, 2022, 2023, 2025 | KY285014.1 | APM84516.1 |
The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility.
Research Article
The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility.
Research Article
Genomic Surveillance of Clinical Pseudomonas aeruginosa Isolates Reveals an Additive Effect of Carbapenemase Production on Carbapenem Resistance.
Research Article
The study identified several beta-lactamase genes, including bla OXA-50, bla OXA-10, bla OXA-488, bla GES-5, bla IMP-1, bla IMP-10, bla NDM-1, bla VIM-2, bla VIM-6, and bla VIM-11, as well as inactivating mutations in the porin gene oprD, which contribute to carbapenem resistance in Pseudomonas aeruginosa isolates from Pakistan.
First report of environmental bla (PAC-1)-carrying Aeromonas enteropelogenes.
Research Article
The study reports the first environmental bla PAC-1 -carrying Aeromonas enteropelogenes strain, highlighting the potential of environmental bacteria as a hidden reservoir for bla PAC-1 and suggesting multiple transmission pathways across different species and sources.
The genomic configurations driving antimicrobial resistance and virulence in colistin resistant Pseudomonas aeruginosa from an Egyptian Tertiary Oncology Hospital.
Research Article
The study identified several AMR genes and mutations in colistin-resistant P. aeruginosa isolates, including blaNDM-1, blaOXA-1028, blaOXA-904, and mutations in phoQ and basR genes associated with colistin resistance.
Emergence and dissemination of bla(KPC-31) and bla(PAC-2) among different species of Enterobacterales in Colombia: a new challenge for the microbiological laboratories.
Research Article
The study identifies blaKPC-31, blaKPC-33, blaKPC-8, and blaPAC-2 as key genes responsible for ceftazidime/avibactam resistance in Enterobacterales isolates in Colombia, highlighting the emergence of these resistance mechanisms and their potential for dissemination.
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