Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
extended-spectrum class A beta-lactamase PME-1
Overview
PME-1, an extended-spectrum β-lactamase identified in Pseudomonas aeruginosa.
PME-1, an extended-spectrum β-lactamase identified in Pseudomonas aeruginosa.
PME-1, an extended-spectrum β-lactamase identified in Pseudomonas aeruginosa.
PME-1, an extended-spectrum β-lactamase identified in Pseudomonas aeruginosa.
PME-1, an extended-spectrum beta-lactamase identified in Pseudomonas aeruginosa.
The study identifies PME-1, a novel extended-spectrum beta-lactamase in Pseudomonas aeruginosa, which confers resistance to ceftazidime, cefotaxime, cefepime, and aztreonam.
Comparative Genomics Reveals Novel Species and Insights into the Biotechnological Potential, Virulence, and Resistance of Alcaligenes.
The study identifies multiple antimicrobial resistance genes in Alcaligenes species, particularly in clinical isolates, highlighting the presence of genes conferring resistance to β-lactams, aminoglycosides, sulfonamides, and other antibiotics.
Domestically Acquired NDM-1-Producing Pseudomonas aeruginosa, Southern California, USA, 2023
The study reports a case of domestically acquired NDM-1-producing Pseudomonas aeruginosa in a transplant patient in southern California, highlighting the presence of multiple resistance genes including blaNDM-1, blaOXA-10, blaOXA-488, blaPDC-35, blaPME-1, aac(6')-Ib9, ant(3”)-IIa, aph(3′)-IIb, aph(3′)-VIa, catB3, catB7, cmlA9, fosA, tet(D), and sul1.
In-depth genome and comparative genome analysis of a metal-resistant environmental isolate Pseudomonas aeruginosa S-8.
The study identified several antibiotic resistance genes in Pseudomonas aeruginosa S-8, including beta-lactamases (ampC, blaTEM, blaSHV, blaCTX-M), efflux pump components (mexB, mexA, oprM, acrB, tolC), and a transcriptional regulator (ampR). These genes contribute to resistance against various antibiotics such as beta-lactams, tetracycline, chloramphenicol, and fluoroquinolones.
Real-time investigation of a Burkholderia cenocepacia bacteraemia outbreak in a Vietnamese intensive care unit.
The study identified acquired antimicrobial resistance genes in B. cenocepacia isolates from a bacteraemia outbreak, including aphA6, blaNDM-1, blaPME-1, sul1, and tetG, which conferred resistance to aminoglycosides, carbapenems, sulfonamides, and tetracyclines. No acquired AMR genes were found in the STNF outbreak isolates.
Variable In Vitro Efficacy of Delafloxacin on Multidrug-Resistant Pseudomonas aeruginosa and the Detection of Delafloxacin Resistance Determinants.
Delafloxacin resistance in Pseudomonas aeruginosa is conferred by multiple QRDR mutations and efflux pumps, including gyrA Thr83Ile, parC Ser87Leu, and MexAB-OprM/MexCD-OprJ. blaNDM-1, blaOXA-488, blaPDC-35, blaOXA-395, blaPDC-36, blaPME-1, blaOXA-905, and blaPDC-8 were identified as beta-lactamase genes in resistant strains.
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