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Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
subclass B3 metallo-beta-lactamase POM-1
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaPOM-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | CARBAPENEM, MEROPENEM +16 |
| Gaza Strip, Lebanon, Europe|United States |
| 2011, 2023, 2024, 2025 |
| EU315252.1 |
| ABY56045.1 |
| blaPOM | Reslit | 1 | Carbapenem, Penicillin +1 | Pseudomonas otitidis +2 | South Korea | 2011 | EU315252|GU002288|GU002289|GU002290|GU002291|GU002292|GU002293|GU002294|GU002295|GU002296|GU002297|GU002298 | - |
| blaPOM-2 | Card DatabaseReference Gene CatalogReslit | 4 | Carbapenem, CARBAPENEM | Pseudomonas otitidis +1 | Europe|United States | 2025 | MK807024.1 | QCE31564.1 |
| blaPOM-18 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273031.1 | YED22474.1 |
| blaPOM-19 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273032.1 | YED22475.1 |
| blaPOM-20 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273033.1 | YED22476.1 |
| blaPOM-21 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273034.1 | YED22477.1 |
| blaPOM-22 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273035.1 | YED22478.1 |
| blaPOM-23 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273037.1 | YED22480.1 |
| blaPOM-24 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273041.1 | YED22484.1 |
| blaPOM-25 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273042.1 | YED22485.1 |
| blaPOM-26 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273043.1 | YED22486.1 |
| blaPOM-27 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PZ273046.1 | YED22489.1 |
| blaPOM-3 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | PX654924.1 | YCB24324.1 |
| blaPOM-4 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | JAZDQK010000003.1 | MEE1892801.1 |
| blaPOM-5 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | JALJXM010000001.1 | MCP1616481.1 |
| blaPOM-6 | Reference Gene Catalog | 1 | CARBAPENEM | Pseudomonas sp. 1D4 | - | - | LXJQ01000006.1 | OEC45580.1 |
| blaPOM-7 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | JBPAKU010000001.1 | MGK8706410.1 |
| blaPOM-8 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | CP082244.1 | QZX85747.1 |
| blaPOM-9 | Reference Gene Catalog | 1 | CARBAPENEM | - | - | - | JAANPK010000062.1 | - |
| blaPOM-10 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | WTFN01000023.1 | MWK56609.1 |
| blaPOM-11 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | CP132337.1 | XAY13782.1 |
| blaPOM-12 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | CP126342.1 | WIF70188.1 |
| blaPOM-13 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | JASDEB010000033.1 | MDI6528921.1 |
| blaPOM-14 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | JAOEBU010000019.1 | MDG9783663.1 |
| blaPOM-15 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | FOJP01000012.1 | SFA63212.1 |
| blaPOM-16 | Reference Gene Catalog | 1 | CARBAPENEM | Metapseudomonas otitidis | - | - | JBLUTW010000003.1 | MFV0885902.1 |
| blaPOM-17 | Reference Gene Catalog | 1 | CARBAPENEM | - | - | - | JBVPDU010000002.1 | - |
Metallo-beta-lactamase production by Pseudomonas otitidis: a species-related trait.
Metallo-beta-lactamase production by Pseudomonas otitidis: a species-related trait.
Pseudomonas otitidis constitutively produces a novel subclass B3 metallo-beta-lactamase, blaPOM, which confers resistance to carbapenems, penicillins, and cephalosporins but not to aztreonam.
Metallo-beta-lactamase production by Pseudomonas otitidis: a species-related trait.
Metallo-beta-lactamase production by Pseudomonas otitidis: a species-related trait.
Pseudomonas otitidis bacteremia in an immunocompromised patient with cellulitis: case report and literature review.
Pseudomonas otitidis was identified as the cause of bacteremia in an immunocompromised patient, demonstrating resistance to carbapenems due to the production of the metallo-beta-lactamase POM-1.
First report of carbapenems encoding multidrug-resistant gram-negative bacteria from a pediatric hospital in Gaza Strip, Palestine.
The study identified multiple carbapenem resistance genes, including bla KPC-2, bla PDC-36/12, and bla POM-1, in multidrug-resistant Gram-negative bacteria isolated from a pediatric hospital in the Gaza Strip. These genes were found in various bacterial species such as Escherichia coli and Klebsiella pneumoniae.
Nationwide surveillance of carbapenem-resistant Gram-negative pathogens in the Lebanese environment.
The study identified carbapenem-resistant Gram-negative bacteria in various environmental samples in Lebanon, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Key resistance genes detected include bla NDM-5, bla OXA-23, bla OXA-66, mexAB-OprM, bla IMP-1, and others, highlighting the widespread presence of carbapenem resistance in the environment.
Establishing Clinical and Laboratory Standards Institute M45 antimicrobial susceptibility testing methods and breakpoints for Pseudomonas other than Pseudomonas aeruginosa.
The study established tentative CLSI M45 antimicrobial susceptibility testing breakpoints for Pseudomonas other than Pseudomonas aeruginosa (POPA). It identified various beta-lactamase genes, including metallo-beta-lactamases (MBLs) such as bla POM-1, bla POM-2, bla PAM-1, bla PST-1, bla VIM-2, bla CARB-2, bla DHA-1, and bla IMP-13, which confer resistance to carbapenems. Additionally, multidrug-resistant efflux pumps like ttgABC and tmexCD-toprJ were found to contribute to carbapenem resistance. Other resistance genes for aminoglycosides, trimethoprim-sulfamethoxazole, quaternary ammonium compounds, chloramphenicol, and fluoroquinolones were also detected.
Establishing Clinical and Laboratory Standards Institute M45 antimicrobial susceptibility testing methods and breakpoints for Pseudomonas other than Pseudomonas aeruginosa.
The study established tentative CLSI M45 antimicrobial susceptibility testing breakpoints for Pseudomonas other than Pseudomonas aeruginosa (POPA). It identified various beta-lactamase genes, including metallo-beta-lactamases (MBLs) such as bla POM-1, bla POM-2, bla PAM-1, bla PST-1, bla VIM-2, bla CARB-2, bla DHA-1, and bla IMP-13, which confer resistance to carbapenems. Additionally, multidrug-resistant efflux pumps like ttgABC and tmexCD-toprJ were found to contribute to carbapenem resistance. Other resistance genes for aminoglycosides, trimethoprim-sulfamethoxazole, quaternary ammonium compounds, chloramphenicol, and fluoroquinolones were also detected.
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