Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
RTG family carbenicillin-hydrolyzing class A beta-lactamase CARB-49
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaCARB-49 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | BETA-LACTAM, AMOXICILLIN +4 | Acinetobacter baumannii | Middle East|Europe|Asia|South America|Peru|Egypt|Saudi Arabia|Denmark|Pakistan|Jordan|Iraq|Lebanon|China|Ghana | 2025 | KX599396.1 | ANW47155.1 |
| blaCARB-50 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | BETA-LACTAM, PENICILLIN BETA-LACTAM +4 | Acinetobacter baumannii | Argentina|Brazil|USA|Germany|Chile|Czech Republic|Hungary|Spain|Turkey|Afghanistan|Ukraine | 2007, 2025 | MG717455.1 | AXH79875.1 |
| blaCARB-8 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, AMOXICILLIN +2 | Oligella urethralis | - | 2003 | AY178993.1 | AAO59455.1 |
| blaCARB-54 | Card DatabaseReference Gene Catalog | 3 | BETA-LACTAM, PENICILLIN BETA-LACTAM | Proteus mirabilis | - | 1991 | D13209.1 | BAA02496.1 |
| blaRTG-4 | Reslit | 1 | cefepime | Acinetobacter baumannii +1 | - | 2009 | EU850412 | - |
| blaCARB-10 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | CEPHALOSPORIN, AMOXICILLIN +6 | Acinetobacter baumannii | Argentina|Brazil|USA|Germany|Chile|Czech Republic|Hungary|Spain|Turkey|Afghanistan|Ukraine | 2009, 2025 | EU850412.1 | ACJ61335.1 |
| blaCARB-14 | Card DatabaseReference Gene CatalogResFinder Database | 4 | BETA-LACTAM, AMOXICILLIN +2 | Acinetobacter baumannii | - | 2012 | JQ364968.1 | AFI72872.1 |
| blaRTG | Reslit | 1 | carbapenems | Acinetobacter baumannii | Germany | 2013 | - | - |
| blaCARB-16 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | BETA-LACTAM, AMOXICILLIN +5 | Psychrobacter maritimus +1 | France, China, Asia|South America|North America|Europe|Africa, Middle East|Europe|Asia|South America|Peru|Egypt|Saudi Arabia|Denmark|Pakistan|Jordan|Iraq|Lebanon|China|Ghana | 2014, 2024, 2025 | HF953351.1 | CCW43444.1 |
| blaCARB-5 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | BETA-LACTAM, AMOXICILLIN +3 | Acinetobacter calcoaceticus subsp. anitratus +1 | Argentina|Canada|Germany|United States | 1989, 2025 | AF135373.1 | AAF61417.1 |
| blaCARB-16/49/5 | Reslit | 1 | beta lactams | Acinetobacter baumannii | Thailand|Nepal | 2020 | PRJEB32181|JABCNM000000000|JABCNJ000000000|JABCNK000000000|JABCNI000000000|JABCNL000000000|JABCNH000000000 | - |
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Research Article
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Research Article
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Research Article
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Research Article
Molecular characterization of class 1 integrons in clinical strains of Salmonella typhimurium isolated in Slovakia.
Research Article
Nucleotide sequence and characterization of a carbenicillin-hydrolyzing penicillinase gene from Proteus mirabilis.
Research Article
Nucleotide sequence and characterization of a carbenicillin-hydrolyzing penicillinase gene from Proteus mirabilis.
Research Article
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Research Article
The study identifies RTG-4, a novel extended-spectrum CARB-type beta-lactamase from Acinetobacter baumannii, which confers resistance to cefepime and cefpirome through hydrolysis.
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Research Article
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Research Article
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Research Article
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Research Article
A novel and hybrid composite transposon at the origin of acquisition of bla(RTG-5) in Acinetobacter baumannii.
Research Article
A novel and hybrid composite transposon at the origin of acquisition of bla(RTG-5) in Acinetobacter baumannii.
Research Article
A novel and hybrid composite transposon at the origin of acquisition of bla(RTG-5) in Acinetobacter baumannii.
Research Article
A novel and hybrid composite transposon at the origin of acquisition of bla(RTG-5) in Acinetobacter baumannii.
Research Article
DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates.
Research Article
The study developed a DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates, identifying numerous resistance genes and mutations associated with carbapenem, aminoglycoside, fluoroquinolone, and other antibiotic resistances.
Genetic structure and biological properties of the first ancient multiresistance plasmid pKLH80 isolated from a permafrost bacterium.
Research Article
Genetic structure and biological properties of the first ancient multiresistance plasmid pKLH80 isolated from a permafrost bacterium.
Research Article
Genetic structure and biological properties of the first ancient multiresistance plasmid pKLH80 isolated from a permafrost bacterium.
Research Article
Genetic structure and biological properties of the first ancient multiresistance plasmid pKLH80 isolated from a permafrost bacterium.
Research Article
Novel carbenicillin-hydrolyzing beta-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus.
Research Article
Novel carbenicillin-hydrolyzing beta-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus.
Research Article
Novel carbenicillin-hydrolyzing beta-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus.
Research Article
Novel carbenicillin-hydrolyzing beta-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus.
Research Article
Genomic analysis reveals high virulence and antibiotic resistance amongst phage susceptible Acinetobacter baumannii.
Research Article
The study identified multiple antibiotic resistance genes in phage-susceptible Acinetobacter baumannii strains, including sulfonamide, tetracycline, beta-lactam, aminoglycoside, macrolide, and phenicol resistance genes. These findings highlight the complex resistance profiles of these strains and their potential implications for therapeutic strategies.
Genomics unveils country-to-country transmission between animal hospitals of a multidrug-resistant and sequence type 2 Acinetobacter baumannii clone.
Research Article
The study identifies several AMR genes and mutations in a multidrug-resistant Acinetobacter baumannii clone, including blaCARB-16, tetA, gyrA, parC, IS26, ABGRI1, ABGRI2, aphA1, strA, and strB, which contribute to resistance against various antibiotics.
Longitudinal genomics reveals carbapenem-resistant Acinetobacter baumannii population changes with emergence of highly resistant ST164 clone.
Research Article
The study identifies the emergence of the highly resistant ST164 clone of Acinetobacter baumannii in an ICU setting, highlighting the presence of multiple carbapenemase genes including bla OXA-23, bla NDM-1, bla CARB-16, and ampC.
Analysis of Acinetobacter P-type type IV secretion system-encoding plasmid diversity uncovers extensive secretion system conservation and diverse antibiotic resistance determinants.
Research Article
This study identified 17 distinct antibiotic resistance genes across 53 P-type T4SS-encoding plasmids in Acinetobacter species, including various beta-lactamases, aminoglycoside modifying enzymes, and others, highlighting the significant diversity of resistance determinants carried by these plasmids.
Phylogenomics, evolution and origin of multidrug-resistant Acinetobacter baumannii ST15.
Research Article
The study identifies multiple carbapenem resistance genes, including blaOXA-23, blaOXA-51, blaOXA-219, blaOXA-58, blaOXA-253, and blaOXA-72, as well as other resistance genes such as aphA6 and sul2, in multidrug-resistant Acinetobacter baumannii ST15 strains.
Phylogenomics, evolution and origin of multidrug-resistant Acinetobacter baumannii ST15.
Research Article
The study identifies multiple carbapenem resistance genes, including blaOXA-23, blaOXA-51, blaOXA-219, blaOXA-58, blaOXA-253, and blaOXA-72, as well as other resistance genes such as aphA6 and sul2, in multidrug-resistant Acinetobacter baumannii ST15 strains.
Comparative genomics of Pseudomonas paraeruginosa.
Research Article
The study identifies various AMR genes and mutations in Pseudomonas paraeruginosa, including carbapenemases like blaVIM-2, blaVIM-6, blaVIM-28, and blaKPC-2, as well as efflux pump genes (mexAB-oprM, mexCD-oprJ, etc.), and mutations in oprD, mexS, mexR, mexZ, lasR, mvfR, and vqsM that contribute to antibiotic resistance.
Global emergence of Acinetobacter baumannii International Clone 12 predominantly found in the Middle East.
Research Article
The study identifies multiple acquired antimicrobial resistance genes in Acinetobacter baumannii International Clone 12, including bla OXA-23, bla GES-11, bla GES-12, bla GES-22, bla GES-35, bla CARB-16, bla CARB-49, aphA6a, aadB, strA, strB, cmlA1, aadA2b, sul1, drfA7, dfrA1, qacE, tet(B), tet(X3), msr(E), mph(E), bla TEM-1B, and aacC3. These genes contribute to resistance against various antibiotics, highlighting the complexity of resistance mechanisms in this clone.
Global emergence of Acinetobacter baumannii International Clone 12 predominantly found in the Middle East.
Research Article
The study identifies multiple acquired antimicrobial resistance genes in Acinetobacter baumannii International Clone 12, including bla OXA-23, bla GES-11, bla GES-12, bla GES-22, bla GES-35, bla CARB-16, bla CARB-49, aphA6a, aadB, strA, strB, cmlA1, aadA2b, sul1, drfA7, dfrA1, qacE, tet(B), tet(X3), msr(E), mph(E), bla TEM-1B, and aacC3. These genes contribute to resistance against various antibiotics, highlighting the complexity of resistance mechanisms in this clone.
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