blaS
beta-lactamase
NCBI Pathogen Isolates
Bacterial genomes carrying this gene
NCBI Reference Gene Catalog
Known alleles and reference sequences
UniProt
Protein entries specific to blaS
AMR Rules
Browse AMR rules for blaS
Validation StatusCandidate
Overview
- Validation Method
- disc diffusion and minimal inhibitory concentration (MIC) assays
- Drug Classes
- beta-lactam antibiotics
- Organisms
- Mycobacterium tuberculosis, Mycobacterium smegmatis
- Papers
- 1
- Databases
- Reslit
Papers1
1
Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics.
The study identifies and characterizes beta-lactamases blaC, blaS, and a putative cephalosporinase blaE in Mycobacterium tuberculosis and Mycobacterium smegmatis, demonstrating their roles in beta-lactam resistance through increased susceptibility in mutants lacking these genes.
Gene Information
- Gene Name
- blaS
- Allele
- blaS
- Encodes
- beta-lactamase
- Source Database
- Reslit
- Confers Resistance To
- beta-lactam antibiotics
- Organisms Tested In
- • Mycobacterium tuberculosis• Mycobacterium smegmatis
- Validation Method
- disc diffusion and minimal inhibitory concentration (MIC) assays
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