Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
carbapenem-hydrolyzing metallo-beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| bla_SPG-1 | Reslit | 2 | meropenem, carbapenems | Sphingomonas sp. +1 | Denmark|United Kingdom|Germany|Spain|Norway|Algeria, Manitoba, Canada | 2016, 2024 | KP109675|KP109676|KP109677|KP109678|KP109679|KP109680|KP109681 | - |
| blaSPG-1 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CARBAPENEM, MEROPENEM +13 | Sphingomonas sp. ALS-13 | - | 2016 | KP109680.1 | AJP77080.1 |
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing beta-lactamases of Potential Clinical Relevance.
Research Article
The study identifies seven new carbapenem-hydrolyzing metallo-beta-lactamases (MBLs) from soil bacteria, including bla_CPS-1, bla_ESP-1, bla_PEDO-1, bla_SPG-1, and bla_MSI-1, which confer resistance to various β-lactam antibiotics when expressed in E. coli.
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing β-Lactamases of Potential Clinical Relevance.
Research Article
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing β-Lactamases of Potential Clinical Relevance.
Research Article
The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing β-Lactamases of Potential Clinical Relevance.
Research Article
Bacterial diversity and resistome analysis of drinking water stored in cisterns from two First Nations communities in Manitoba, Canada.
Research Article
The study identified a diverse array of antimicrobial resistance genes in drinking water stored in cisterns from two First Nations communities in Manitoba, Canada. Key findings include the presence of genes such as aac(3')-Ia, aac(6')-Iia, aac(6')-Iic, aph(3')-Ia, acrD, smeB, smeR, FEZ-1, rm3, SPG-1, OXA-21, OXA-119, OXA-205, dfrA14, dfrB6, acrB, acrF, adeF, ceoB, emrA, mexE, mexF, mexI, oprN, oqxB, BRP(MBL), vanSO, axyY, CRP, efrB, macB, mexB, mexC, mexD, mexK, mexQ, mexW, mexY, mtrA, muxB, muxC, oleB, oleC, ompB, oprM, smeD, smeE, golS, mdsB, PER-2, TEM-126, msbA, arnA, bacA, bcrA, MCR-5, rosA, rosB, rpoB2, ugd, mexN, taeA, efpA, rphA, rphB, otr(A), otrC, tetA(48 ), ompH, and triC, which confer resistance to various antibiotics including aminoglycosides, beta-lactams, cephalosporins, carbapenems, fluoroquinolones, macrolides, monobactams, nitroimidazoles, peptides, phenicols, pleuromutilins, rifamycins, tetracyclines, and triclosan.
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