blaTEM

The study identifies TEM-52 as the most prevalent extended-spectrum beta-lactamase (ESBL) in clinical isolates of Escherichia coli and Klebsiella pneumoniae in Korea.

The study characterizes several novel TEM-type β-lactamases in Proteus mirabilis, including TEM-57, TEM-66, TEM-65, TEM-73, and TEM-74, along with previously known variants such as TEM-1, TEM-2, TEM-3, TEM-24, and TEM-44. These enzymes exhibit varying degrees of resistance to β-lactam antibiotics, particularly amoxicillin, ticarcillin, piperacillin, and cephalothin, with some showing extended-spectrum activity against broader classes of β-lactams.

The study characterizes several novel TEM-type β-lactamases in Proteus mirabilis, including TEM-57, TEM-66, TEM-65, TEM-73, and TEM-74, along with previously known variants such as TEM-1, TEM-2, TEM-3, TEM-24, and TEM-44. These enzymes exhibit varying degrees of resistance to β-lactam antibiotics, particularly amoxicillin, ticarcillin, piperacillin, and cephalothin, with some showing extended-spectrum activity against broader classes of β-lactams.

The study characterizes several novel TEM-type β-lactamases in Proteus mirabilis, including TEM-57, TEM-66, TEM-65, TEM-73, and TEM-74, along with previously known variants such as TEM-1, TEM-2, TEM-3, TEM-24, and TEM-44. These enzymes exhibit varying degrees of resistance to β-lactam antibiotics, particularly amoxicillin, ticarcillin, piperacillin, and cephalothin, with some showing extended-spectrum activity against broader classes of β-lactams.

The study identified a plasmid-encoded extended-spectrum beta-lactamase, TEM-17, in Capnocytophaga ochracea, which confers resistance to various beta-lactam antibiotics.

The study identifies TEM-68, a novel complex mutant beta-lactamase in a Klebsiella pneumoniae isolate, which exhibits both extended-spectrum beta-lactamase (ESBL) and inhibitor resistance (IR) activities.

The study identified various beta-lactamase genes including TEM-1, TEM-2, TEM-3, TEM-66, CARB-2, SHV-1, IRT-13, IRT-16, and IRT-2 in Proteus mirabilis strains, highlighting their role in beta-lactam resistance.

The study identified various beta-lactamase genes including TEM-1, TEM-2, TEM-3, TEM-66, CARB-2, SHV-1, IRT-13, IRT-16, and IRT-2 in Proteus mirabilis strains, highlighting their role in beta-lactam resistance.

The study identified various beta-lactamase genes including TEM-1, TEM-2, TEM-3, TEM-66, CARB-2, SHV-1, IRT-13, IRT-16, and IRT-2 in Proteus mirabilis strains, highlighting their role in beta-lactam resistance.

The study identified various beta-lactamase genes including TEM-1, TEM-2, TEM-3, TEM-66, CARB-2, SHV-1, IRT-13, IRT-16, and IRT-2 in Proteus mirabilis strains, highlighting their role in beta-lactam resistance.

The study identifies TEM-1 and TEM-12 beta-lactamases as key players in antibiotic resistance, demonstrating that small phenotypic differences in these enzymes can lead to significant resistance variations depending on antibiotic concentration.

The study identifies TEM-1 and TEM-12 beta-lactamases as key players in antibiotic resistance, demonstrating that small phenotypic differences in these enzymes can lead to significant resistance variations depending on antibiotic concentration.

The study identifies TEM-72, a new extended-spectrum beta-lactamase in Proteus mirabilis and Morganella morganii, which confers resistance to various beta-lactam antibiotics.

The study identified new genetic features of blaTEM genes in amoxicillin-clavulanate-resistant Escherichia coli isolates, including novel mutations and promoter variations that contribute to resistance.

The study identified new genetic features of blaTEM genes in amoxicillin-clavulanate-resistant Escherichia coli isolates, including novel mutations and promoter variations that contribute to resistance.

The study identified new genetic features of blaTEM genes in amoxicillin-clavulanate-resistant Escherichia coli isolates, including novel mutations and promoter variations that contribute to resistance.

The study identified new genetic features of blaTEM genes in amoxicillin-clavulanate-resistant Escherichia coli isolates, including novel mutations and promoter variations that contribute to resistance.

The study identified new genetic features of blaTEM genes in amoxicillin-clavulanate-resistant Escherichia coli isolates, including novel mutations and promoter variations that contribute to resistance.

The study identified multiple extended-spectrum beta-lactamase (ESBL) genes, including bla TEM-53, bla TEM-63, and novel bla SHV variants (SHV-19 to SHV-22), in Klebsiella pneumoniae isolates from a South African hospital.

The study identified multiple extended-spectrum beta-lactamase (ESBL) genes, including bla TEM-53, bla TEM-63, and novel bla SHV variants (SHV-19 to SHV-22), in Klebsiella pneumoniae isolates from a South African hospital.

The study identifies SHV-14, a novel beta-lactamase variant in Klebsiella pneumoniae isolates, and TEM-29, a known extended-spectrum beta-lactamase, as contributors to beta-lactam resistance.

The study identifies a new TEM variant, TEM-92, produced by Proteus mirabilis and Providencia stuartii isolates, which exhibits resistance to ceftazidime and cefotaxime.

The study identifies a plasmid encoding SHV-12, TEM-1, and a variant of IMP-2 metallo-beta-lactamase, IMP-8, from a clinical isolate of Klebsiella pneumoniae. IMP-8 differs from IMP-2 by four nucleotide substitutions leading to two amino acid changes and is carried on an integron-borne gene cassette.

The study identifies two novel beta-lactamases, SHV-25 and SHV-26, in Klebsiella pneumoniae isolates from northern Taiwan. SHV-25 is a non-ESBL, while SHV-26 exhibits reduced susceptibility to clavulanic acid.

The study characterizes the novel TEM-type ESBL TEM-88 and compares its biochemical characteristics to those of TEM-15 and TEM-52, identifying their resistance profiles against various beta-lactam antibiotics.

The study characterizes the novel TEM-type ESBL TEM-88 and compares its biochemical characteristics to those of TEM-15 and TEM-52, identifying their resistance profiles against various beta-lactam antibiotics.

The study characterizes the novel TEM-type ESBL TEM-88 and compares its biochemical characteristics to those of TEM-15 and TEM-52, identifying their resistance profiles against various beta-lactam antibiotics.

The study identifies multiple Klebsiella pneumoniae clones carrying TEM-4, SHV-2, SHV-2a, SHV-5, CTX-M-10, and CTX-M-9 extended-spectrum beta-lactamases, highlighting the clonal diversity and spread of these resistance genes in a single hospital over a 12-year period.

The study identifies TEM-87, a new extended-spectrum beta-lactamase in Proteus mirabilis, which shows resistance to ceftazidime, aztreonam, and oxyimino cephalosporins.

The study identified three distinct extended-spectrum beta-lactamases (ESBLs): CTX-M-10, TEM-24, and TEM-27, which were responsible for resistance to extended-spectrum cephalosporins in Enterobacter isolates.

The study identified three distinct extended-spectrum beta-lactamases (ESBLs): CTX-M-10, TEM-24, and TEM-27, which were responsible for resistance to extended-spectrum cephalosporins in Enterobacter isolates.

The study identifies TEM-80, a novel inhibitor-resistant beta-lactamase in clinical isolates of Enterobacter cloacae and Escherichia coli, which confers resistance to ampicillin, amoxicillin, ticarcillin, and cephalothin.

The study identifies several extended-spectrum beta-lactamases (ESBLs) including TEM-52, SHV-2a, TEM-88, CMY-1-like, and CTX-M-14 in Escherichia coli and Klebsiella pneumoniae isolates from children with bloodstream infections. These ESBLs confer resistance to various beta-lactam antibiotics.

The study identifies several extended-spectrum beta-lactamases (ESBLs) including TEM-52, SHV-2a, TEM-88, CMY-1-like, and CTX-M-14 in Escherichia coli and Klebsiella pneumoniae isolates from children with bloodstream infections. These ESBLs confer resistance to various beta-lactam antibiotics.

The study identifies TEM-71, a novel plasmid-encoded extended-spectrum beta-lactamase from a clinical isolate of Klebsiella pneumoniae, which exhibits resistance to multiple beta-lactam antibiotics including ceftazidime, cefotaxime, and aztreonam.

The study identifies a novel plasmid-encoded class C beta-lactamase, MOX-2, in a multidrug-resistant Klebsiella pneumoniae isolate from Greece, which exhibits high hydrolytic activity against various beta-lactam antibiotics.

The study identified blaTEM-1 and blaPER-1 beta-lactamase genes as contributors to beta-lactam resistance in Acinetobacter baumannii. The chromosomal AmpC beta-lactamase was found to play a significant role in resistance, while changes in outer membrane proteins were linked to carbapenem resistance.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies various TEM-type beta-lactamase genes, including novel variants such as bla TEM-95b, which confers resistance to ampicillin and ticarcillin in Escherichia coli isolates from diverse sources.

The study identifies a new TEM variant, TEM-103/IRT-28, which confers resistance to penicillins and is resistant to β-lactamase inhibitors due to the Arg 275 Leu substitution.

The study reports the first inhibitor-resistant TEM-derived beta-lactamase (TEM-30, IRT-2) identified in Portugal, which shows resistance to amoxicillin and ticarcillin, and a nucleotide substitution (C929→A) leading to Arg244→Ser amino acid change.

The study identified blaTEM-1 and blaOXA-30 as the primary genes responsible for decreased susceptibility to cefpodoxime in E. coli, with additional contributions from porin alterations.

The study identifies blaTEM-67, a novel inhibitor-resistant beta-lactamase gene from Proteus mirabilis, which was integrated into the Escherichia coli chromosome. This gene confers resistance to amoxicillin and amoxicillin-clavulanic acid.

The study identifies and characterizes the class 1 integron In34, which contains multiple antibiotic resistance genes including aadB, dfrA10, aphA1, catA1, blaTEM, and sul1. These genes confer resistance to various antibiotics such as gentamicin, kanamycin, tobramycin, trimethoprim, chloramphenicol, ampicillin, and sulfamethoxazole.

The study identifies a new TEM-derived extended-spectrum beta-lactamase, TEM-91, which confers resistance to ceftazidime through specific amino acid substitutions.

A novel extended-spectrum beta-lactamase, TEM-26, was identified as the cause of ceftazidime resistance in isolates from cancer patients. This enzyme hydrolyzes ceftazidime, aztreonam, and penicillins.

The study identifies various extended-spectrum beta-lactamases (ESBLs) including TEM-24b, TEM-21, TEM-15, TEM-19, TEM-3, SHV-4, and CTX-M-1, which confer resistance to multiple beta-lactam antibiotics in Enterobacteriaceae isolates from community and private healthcare centers.

The study identifies various extended-spectrum beta-lactamases (ESBLs) including TEM-24b, TEM-21, TEM-15, TEM-19, TEM-3, SHV-4, and CTX-M-1, which confer resistance to multiple beta-lactam antibiotics in Enterobacteriaceae isolates from community and private healthcare centers.

The study identifies various extended-spectrum beta-lactamases (ESBLs) including TEM-24b, TEM-21, TEM-15, TEM-19, TEM-3, SHV-4, and CTX-M-1, which confer resistance to multiple beta-lactam antibiotics in Enterobacteriaceae isolates from community and private healthcare centers.

The study identifies various extended-spectrum beta-lactamases (ESBLs) including TEM-24b, TEM-21, TEM-15, TEM-19, TEM-3, SHV-4, and CTX-M-1, which confer resistance to multiple beta-lactam antibiotics in Enterobacteriaceae isolates from community and private healthcare centers.

The study identifies various extended-spectrum beta-lactamases (ESBLs) including TEM-24b, TEM-21, TEM-15, TEM-19, TEM-3, SHV-4, and CTX-M-1, which confer resistance to multiple beta-lactam antibiotics in Enterobacteriaceae isolates from community and private healthcare centers.

The study identified CTX-M-9, CMY-2, and TEM-1 beta-lactamase genes in extended-spectrum cephalosporin-resistant Escherichia coli (ESCREC) isolates from a summer camp outbreak. These genes conferred resistance to various β-lactam antibiotics.

The study identifies two novel oxacillinases, OXA-48 and OXA-47, which confer resistance to imipenem and ceftazidime, respectively, in a multidrug-resistant Klebsiella pneumoniae isolate.

The study identifies several extended-spectrum beta-lactamases (ESBLs) in Canadian hospitals, including novel variants such as TEM-115, TEM-120, SHV-40, SHV-41, and SHV-42, highlighting the diversity and emergence of these resistance mechanisms in Escherichia coli and Klebsiella spp.

The study identifies several extended-spectrum beta-lactamases (ESBLs) in Canadian hospitals, including novel variants such as TEM-115, TEM-120, SHV-40, SHV-41, and SHV-42, highlighting the diversity and emergence of these resistance mechanisms in Escherichia coli and Klebsiella spp.

The study identifies several extended-spectrum beta-lactamases (ESBLs) in Canadian hospitals, including novel variants such as TEM-115, TEM-120, SHV-40, SHV-41, and SHV-42, highlighting the diversity and emergence of these resistance mechanisms in Escherichia coli and Klebsiella spp.

The study identifies several extended-spectrum beta-lactamases (ESBLs) in Canadian hospitals, including novel variants such as TEM-115, TEM-120, SHV-40, SHV-41, and SHV-42, highlighting the diversity and emergence of these resistance mechanisms in Escherichia coli and Klebsiella spp.

The study identifies several extended-spectrum beta-lactamases (ESBLs) in Canadian hospitals, including novel variants such as TEM-115, TEM-120, SHV-40, SHV-41, and SHV-42, highlighting the diversity and emergence of these resistance mechanisms in Escherichia coli and Klebsiella spp.

The study identifies several extended-spectrum beta-lactamases (ESBLs) in Canadian hospitals, including novel variants such as TEM-115, TEM-120, SHV-40, SHV-41, and SHV-42, highlighting the diversity and emergence of these resistance mechanisms in Escherichia coli and Klebsiella spp.

The study identified various beta-lactamases, including TEM-type, CMY-2, and OXA-type, in amoxicillin-clavulanate-resistant Escherichia coli isolates. Notably, two isolates harbored inhibitor-resistant TEM enzymes (TEM-34 and TEM-122) that conferred resistance to amoxicillin-clavulanate.

The study identifies SHV-12-like extended-spectrum beta-lactamase-producing strains of Salmonella enterica serotypes Babelsberg and Enteritidis isolated in France among infants adopted from Mali. The SHV-12 beta-lactamase was found to confer resistance to cephalosporins, while TEM beta-lactamase conferred resistance to penicillins and cephalosporins.

The study identified CTX-M-3, TEM-47, and SHV-5 extended-spectrum beta-lactamases in Serratia marcescens isolates from two hospitals in Danzig, Poland, over a 5-year period. These enzymes conferred resistance to various beta-lactam antibiotics.

The study describes a DNA microarray for the rapid genotyping of TEM beta-lactamases, enabling the identification of single nucleotide polymorphisms (SNPs) in 96% of the TEM beta-lactamase variants related to extended-spectrum beta-lactamase (ESBL) and inhibitor-resistant TEM (IRT) phenotypes.

The study reports the complete nucleotide sequence of a 92-kilobase plasmid, pC15-1a, which harbors the CTX-M-15 extended-spectrum beta-lactamase, along with other resistance genes such as blaOXA-1, blaTEM-1, aac(6')-Ib, aac(3)-II, and tetA. These genes contribute to multidrug resistance in Escherichia coli strains associated with an outbreak in long-term-care facilities in Toronto, Canada.

The study reports the first detection of bla CTX-M-15 in Salmonella and identifies multiple beta-lactamase genes (bla TEM-1b, bla SHV-5, bla CTX-M-15, and bla CMY-2) in a multidrug-resistant Salmonella enterica serotype Infantis isolate from Honduras.

The study reports the first documented outbreak of CTX-M-producing E. coli in a long-term care facility in France, highlighting the emergence of these strains and their resistance mechanisms.

The study identifies TEM-63 and a novel TEM enzyme, TEM-131, in nontyphoidal Salmonella isolates from South Africa, highlighting their role in resistance to extended-spectrum cephalosporins.

The study identifies TEM-63 and a novel TEM enzyme, TEM-131, in nontyphoidal Salmonella isolates from South Africa, highlighting their role in resistance to extended-spectrum cephalosporins.

The study identifies TEM-121, a novel complex mutant TEM-type beta-lactamase from Enterobacter aerogenes, which exhibits unique resistance properties against ceftazidime and aztreonam while showing reduced susceptibility to clavulanic acid.

The study identifies several AMR genes in multidrug-resistant Salmonella enterica serovar Muenchen isolates from pigs and humans, including blaOXA-30, aadA2, aphA1-Iab, tetA(B), blaTEM, strA, cmlA, and tetA(A). These genes confer resistance to various antibiotics such as ampicillin, amoxicillin-clavulanic acid, streptomycin, kanamycin, tetracycline, chloramphenicol, and gentamicin.

The study identified the presence of extended-spectrum beta-lactamases (ESBLs) in Enterobacter isolates, including TEM-1, SHV-12, CTX-M-2, and CTX-M-26, which confer resistance to various beta-lactam antibiotics.

The study identifies multiple antimicrobial resistance genes on plasmids pSC138 and pSCV50 in Salmonella enterica serovar Choleraesuis SC-B67, including blaTEM-1, blaCMY-2, tetRA, strA, aadA2, sulI, sulII, catI, cmlA, aph, sat, mef, mer, ebr, qac, and blaTEM-67. Additionally, mutations in the chromosomal genes gyrA and parC, along with the inactivation of acrR, contribute to ciprofloxacin resistance.

The study identifies multiple antimicrobial resistance genes on plasmids pSC138 and pSCV50 in Salmonella enterica serovar Choleraesuis SC-B67, including blaTEM-1, blaCMY-2, tetRA, strA, aadA2, sulI, sulII, catI, cmlA, aph, sat, mef, mer, ebr, qac, and blaTEM-67. Additionally, mutations in the chromosomal genes gyrA and parC, along with the inactivation of acrR, contribute to ciprofloxacin resistance.

The study identifies a novel TEM-type extended-spectrum beta-lactamase, TEM-134, in a Citrobacter koseri clinical isolate, which shows resistance to ceftazidime and cefotaxime.

The study identifies four novel TEM-type extended-spectrum beta-lactamases (TEM-85, TEM-86, TEM-93, and TEM-94) in clinical Enterobacteriaceae strains in Poland, demonstrating their resistance to ceftazidime and cefotaxime.

The study identifies four novel TEM-type extended-spectrum beta-lactamases (TEM-85, TEM-86, TEM-93, and TEM-94) in clinical Enterobacteriaceae strains in Poland, demonstrating their resistance to ceftazidime and cefotaxime.

The study identifies four novel TEM-type extended-spectrum beta-lactamases (TEM-85, TEM-86, TEM-93, and TEM-94) in clinical Enterobacteriaceae strains in Poland, demonstrating their resistance to ceftazidime and cefotaxime.

The study identifies four novel TEM-type extended-spectrum beta-lactamases (TEM-85, TEM-86, TEM-93, and TEM-94) in clinical Enterobacteriaceae strains in Poland, demonstrating their resistance to ceftazidime and cefotaxime.

The study identified the dominant extended-spectrum beta-lactamase SHV-2a and characterized the novel TEM-132 enzyme in Enterobacteriaceae isolates from a Slovak hospital.

The study identifies TEM-126, a novel TEM-type extended-spectrum beta-lactamase with the mutations Asp179Glu and Met182Thr, which confers resistance to ceftazidime.

The study identifies TEM-109, a novel complex mutant beta-lactamase combining substitutions from TEM-6 and TEM-33, which confers resistance to amoxicillin, ticarcillin, and ceftazidime.