Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
metallo-beta-lactamase
Overview
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
The study characterizes the blaB, blaB2, and blaB3 genes, which encode metallo-beta-lactamases in Chryseobacterium (Flavobacterium) meningosepticum, contributing to carbapenem resistance.
Development and evaluation of fARGene, a computational tool for the detection of antibiotic resistance genes in metagenomic data
The study presents fARGene, a method for identifying and reconstructing antibiotic resistance genes from metagenomic data, demonstrating the detection of 221 ARGs, 58 of which were previously unreported, with 81% providing a resistance phenotype in E. coli.
New Beta-lactamases in Candidate Phyla Radiation: Owning Pleiotropic Enzymes Is a Smart Paradigm for Microorganisms with a Reduced Genome.
The study identified five putative beta-lactamase-encoding genes from the CPR resistome, which exhibited hydrolytic activity against certain beta-lactam antibiotics and RNA. These enzymes were expressed in E. coli and characterized using biochemical assays.
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