blacarba

carbapenemase

Validation StatusCandidate

Overview

Validation Method: sequence analysis and functional characterization
Drug Classes: Carbapenem
Organisms: Enterobacter cloacae, Serratia marcescens, Klebsiella pneumoniae, Serratia fonticola, Pseudomonas fluorescens
Papers: 1
Databases: Reslit

Papers1

Molecular Characteristics of Class A β-Lactamases

The paper characterizes various class A β-lactamases, including TEM-1, GIL-1, OXY, CTX-M, SFO-1, CARBA, GES, PER-1, and VEB-1, highlighting their roles in conferring resistance to β-lactam antibiotics such as penicillins, cephalosporins, and carbapenems.

Gene Information

Gene Name: blacarba
Allele: blaCARBA
Encodes: carbapenemase
Source Database: Reslit
Confers Resistance To: Carbapenem
Organisms Tested In: • Enterobacter cloacae
• Serratia marcescens
• Klebsiella pneumoniae
• Serratia fonticola
• Pseudomonas fluorescens
Validation Method: sequence analysis and functional characterization

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blacarba

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