Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
S. Enteritidis and S. Typhimurium Harboring SPI-1 and SPI-2 Are the Predominant Serotypes Associated With Human Salmonellosis in Saudi Arabia.
The study identified the presence of bla TEM−1, bla OXA−1, bla CTX−M−1 group, bla CTX−M−9 group, and bla OXA−48 genes in Salmonella isolates, which confer resistance to various antibiotics. Additionally, mutations in gyrA and parC genes were associated with ciprofloxacin resistance.
An Outbreak of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae in an Intensive Care Unit of a Major Teaching Hospital in Wenzhou, China.
The study identified carbapenem-resistant and hypervirulent Klebsiella pneumoniae isolates carrying bla KPC−2, aac(3')-Ia, aac(6')-Ib, ANT(3')-Ia, rmtB, rmtC, qnrB, qnrS, oqxA, bla SHV−11, bla CTX−M−2 group, bla CTX−M−9 group, bla TEM−1, bla CMY−2, and bla DHA genes, contributing to multidrug resistance.
A Pilot Study of Chicago Waterways as Reservoirs of Multidrug-Resistant Enterobacteriaceae (MDR-Ent) in a High-Risk Region for Community-Acquired MDR-Ent Infection in Children.
The study identified various multidrug-resistant Enterobacteriaceae (MDR-Ent) in Chicago waterways, including genes encoding beta-lactamases (CTX-M-1, CTX-M-9, SHV-ESBL, CMY-II-AmpC), aminoglycoside modifying enzymes (aac-6'-Ib), quinolone resistance proteins (qnrB), efflux pump components (oqxA/B), and colistin resistance (mcr-1). These genes were found in E. coli, K. pneumoniae, and E. cloacae isolates and conferred resistance to multiple antibiotics.
Development and Validation of a Point-of-Care Platform for Rapid Detection of ESBL and Carbapenemase Genes Using URECA-LAMP
The study presents a novel machine-learning-aided platform called URECA-LAMP for the rapid detection of ESBLs and carbapenemases in clinical isolates and urine samples. The platform uses LAMP technology combined with a smartphone application for automated interpretation of results, achieving high agreement rates with WGS results.
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