blalen17

beta-lactamase

Validation StatusCandidate

Overview

Mechanism: hydrolysis of beta-lactam antibiotics
Validation Method: hybrid assembly and AMR prediction
Drug Classes: Ampicillin
Organisms: Klebsiella variicola DSM 15968, Klebsiella variicola
Papers: 2
Databases: Reslit

Papers2

Benchmarking hybrid assembly approaches for genomic analyses of bacterial pathogens using Illumina and Oxford Nanopore sequencing.

PMID 32928108 · 2020

The study compared hybrid assembly approaches for bacterial pathogen genomes and identified AMR genes such as blaZ, msr(A), and tet(K) in Staphylococcus aureus.

Gene Information

Gene Name: blalen17
Allele: blaLEN17
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: Ampicillin
Organisms Tested In: • Klebsiella variicola DSM 15968
Validation Method: hybrid assembly and AMR prediction

Phenotypic and genomic changes in enteric Klebsiella populations during long-term ICU patient hospitalization: the role of RamR regulation.

PMID 39611855 · 2024

Gene Information

Gene Name: blalen17
Allele: blaLEN17
Encodes: chromosomal beta-lactamase
Source Database: Reslit
Mechanism: hydrolysis of beta-lactam antibiotics
Organisms Tested In: • Klebsiella variicola
Validation Method: whole-genome sequencing

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blalen17

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