Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
S. Enteritidis and S. Typhimurium Harboring SPI-1 and SPI-2 Are the Predominant Serotypes Associated With Human Salmonellosis in Saudi Arabia.
The study identified the presence of bla TEM−1, bla OXA−1, bla CTX−M−1 group, bla CTX−M−9 group, and bla OXA−48 genes in Salmonella isolates, which confer resistance to various antibiotics. Additionally, mutations in gyrA and parC genes were associated with ciprofloxacin resistance.
Insights on the performance of phenotypic tests versus genotypic tests for the detection of carbapenemase-producing Gram-negative bacilli in resource-limited settings.
The study evaluated the performance of phenotypic tests (MHT, mCIM, BCT, CDT) versus genotypic tests for detecting carbapenemase-producing Gram-negative bacilli (CPO). It identified bla KPC, bla NDM, bla VIM, bla GIM, and bla OXA−48 as the most prevalent carbapenemase genes among the isolates.
Phenotypic and Genotypic Analysis of Bacterial Pathogens Recovered from Patients Diagnosed with Fever of Unknown Origin in Egypt.
The study identified bla OXA−48, bla VIM, bla IMP, bla TEM, bla CTX-M, aac(6′)-Ib, and bla SHV as prevalent resistance genes in multidrug-resistant (MDR) bacterial isolates from patients with fever of unknown origin in Egypt.
A challenging case of carbapenem resistant Klebsiella pneumoniae-related pyogenic liver abscess with capsular polysaccharide hyperproduction: a case report.
The case report describes the acquisition of the bla OXA−48 gene in a carbapenem-susceptible K. pneumoniae strain during imipenem treatment, leading to carbapenem resistance. The study suggests that imipenem may promote resistance to carbapenems and colistin in K. pneumoniae.
Molecular characterization and epidemiological investigation of colistin resistance in carbapenem-resistant Klebsiella pneumoniae in a tertiary care hospital in Tehran, Iran.
The study identified mcr-1 as a cause of colistin resistance in CRKP isolates and characterized multiple carbapenemase genes, including bla OXA−48, bla KPC, bla VIM, bla IMP, and bla NDM.
Occurrence of Extended-spectrum β-lactamase (ESBL) and Carbapenemase-producing Escherichia coli isolated from Childhood Diarrhoea in Yaoundé, Cameroon.
The study identified several AMR genes, including bla CTX−M, bla TEM, bla OXA−48, tet(A), and tet(B), in ESBL-producing E. coli isolates from childhood diarrhoea in Yaoundé, Cameroon. These genes confer resistance to various antibiotics, highlighting the urgent need for improved surveillance and antimicrobial stewardship.
Genomic dynamics of high-risk carbapenem-resistant klebsiella pneumoniae clones carrying hypervirulence determinants in Egyptian clinical settings.
The study identifies high-risk, extensively carbapenem-resistant Klebsiella pneumoniae strains carrying hypervirulence determinants in Egyptian clinical settings, highlighting the emergence of convergent strains with multiple resistance and virulence genes.
Detection of carbapenemases in Enterobacterales and other Gram-negative bacilli recovered from hospital and municipal wastewater in Mexico City.
The study identified several carbapenemase genes, including bla KPC, bla NDM, bla VIM−2, bla OXA−48, bla NDM−1, and bla NDM−5, in various Gram-negative bacteria from hospital and municipal wastewater in Mexico City.
Cefiderocol-resistant pathogens in German hospital wastewater: a reservoir for multidrug resistance.
The study identifies multiple AMR genes, including bla NDM−1, bla VIM−1, bla OXA−48, and bla KPC−2, in cefiderocol-resistant isolates from German hospital wastewater, highlighting the presence of multidrug-resistant pathogens with diverse resistance mechanisms.
A quantitative characterization of antibiotic resistance and its influencing factors in hospital wastewaters across Lebanon.
The study identifies multiple antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in hospital wastewaters across Lebanon, highlighting the prevalence of resistance to beta-lactams, aminoglycosides, tetracyclines, sulfonamides, and glycopeptides.
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